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超氧化物歧化酶来源于牛红细胞,Superoxide Dismutase from bovine erythrocytes [SOD];BioUltra, lyophilized powder, ≥4,500 units/mg protein, ≥97% (SDS-PAGE)

别名:SOD;过氧化物歧化酶;超氧化物:超氧化物氧化还原酶;Superoxide: superoxide oxidoreductase

CAS号 9054-89-1 Enzyme Commission (EC) Number 1.15.1.1 ( BRENDA | IUBMB ) EINECS 编号 232-943-0 MDL number MFCD00132404 NACRES NA.54
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): S7446
CAS号: 9054-89-1
MDL号: MFCD00132404
增值税发票 √ 免费货运 [顺丰 联邦] √
¥1,963.89

产品描述

General description

Superoxide dismutases are a group of low molecular weight metalloproteins present in all aerobic cells of plants, animals and micro-organisms. They provide protection against damaging reactions with the superoxide radical anion (O2-) by catalyzing its disproportionation into oxygen and hydrogen peroxide.

Application

Superoxide Dismutase from bovine erythrocytes has been used in a study to assess activity parameters in adjuvant-induced arthritis. [1] Superoxide Dismutase from bovine erythrocytes has also been used in a study to simplify the process of purifying superoxide dismutases using charge-controlled hydrophobic chromatography on 10-carboxydecyl Sepharose. [2]

包装

15000, 75000 units in glass bottle

Biochem/physiol Actions

催化超氧化物自由基的歧化反应生成过氧化氢和分子氧。在细胞防御氧自由基的毒性作用方面发挥着重要作用。与一氧化氮(NO)竞争超氧化物阴离子(可与NO反应生成过亚硝酸盐),因此SOD能促进NO的活性。在培养的大鼠卵泡、神经细胞系和转基因小鼠中,SOD也表现出抑制细胞凋亡的作用。

Unit Definition

One unit will inhibit reduction of cytochrome c by 50% in a coupled system with xanthine oxidase at pH 7.8 at 25 °C in a 3.0 mL reaction volume. Xanthine oxidase concentration should produce an initial ΔA550 of 0.025 ± 0.005 per min.

性质

Quality Level200
product lineBioUltra
assay≥97% (SDS-PAGE)
formlyophilized powder
specific activity≥4,500 units/mg protein
mol wt32.5 kDa
compositionProtein, ≥95% biuret
relevant disease(s)arthritis
storage temp.−20°C


安全信息

个人防护装备 EyeshieldsGlovestype N95 (US)
RIDADR NONH for all modes of transport
WGK德国 WGK 3
商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 88 | 欧洲Eur. ≥ 126 | 東京Tokyo ≥ 46 | 香港与北京 ≥ 62