诺地尼-1，Nodinitib-1 [ML130]；≥98% (HPLC)

图片 诺地尼-1，Nodinitib-1 [ML130]；≥98% (HPLC)
别名：1-对甲苯磺酰-1H-苯并[D]咪唑-2-胺；1-[(4-甲基苯基)磺酰基]-1H-苯并咪唑-2-胺；1-[(4-Methylphenyl)sulfonyl]-1H-benzimidazol-2-amine, CID-1088438, ML130

Empirical Formula (Hill Notation): C14H13N3O2S CAS号: 799264-47-4 分子量: 287.34 MDL编号: MFCD04322367 PubChem化学物质编号: 329825379 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: SML0379
CAS号: 799264-47-4
MDL号: MFCD04322367
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说明

生化/生理作用

Nodinitib-1 (ML130) is a selectiove inhibitor of of the nucleotide oligomerization domain (NOD)-1 receptor, which is involved in innate immune response and has been associated with several inflammatory diseases. NOD1 and NOD2 recognize distinct structures derived from bacterial peptidoglycans and directly activate NF-?B pathway, which controls the production of proinflammatory molecules. Nodinitib-1 has 40:1 selectivity for NOD1 over NOD2.
 
 

属性

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

颜色

white to beige

溶解性

DMSO: >10 mg/mL

储存温度

2-8°C

SMILES string

NC1=NC2=C(N1S(C3=CC=C(C)C=C3)(=O)=O)C=CC=C2

InChI

1S/C14H13N3O2S/c1-10-6-8-11(9-7-10)20(18,19)17-13-5-3-2-4-12(13)16-14(17)15/h2-9H,1H3,(H2,15,16)

InChI key

SRFABRWQVPCPRG-UHFFFAOYSA-N

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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