(S,R)-Noscapine is a phthalideisoquinoline alkaloid found in opium. It is an antimicrotubule agent that also shows potent antitumor activity.
Noscapine may be used as a source to synthesize its bromo-derivatives, which has higher tubulin binding activity when compared to noscapine. Its 3,4,5-trimethoxybenzyl analog is a potential antitumor agent.
5 g in glass bottle
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 363960.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
|Quality Level ||100|
|optical activity ||[α]20/D −200°, c = 1 in chloroform|
|mp ||174-176 °C (lit.)|
|SMILES string ||COc1ccc2C(OC(=O)c2c1OC)C3N(C)CCc4cc5OCOc5c(OC)c34|
|InChI key ||AKNNEGZIBPJZJG-MSOLQXFVSA-N|
靶器官 Central nervous system
RIDADR NONH for all modes of transport