诺司卡品 [那可汀]，(S,R)-Noscapine；97%

图片 诺司卡品 [那可汀]，(S,R)-Noscapine；97%
别名：那可丁，(S)-6,7-dimethoxy-3-((R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)isobenzofuran-1(3H)-one；HSDB3372；NSC5366

Empirical Formula (Hill Notation): C22H23NO7 CAS号: 128-62-1 分子量: 413.42 EC 号: 204-899-2 MDL编号: MFCD00069316 PubChem化学物质编号: 24862408 NACRES: NA.22
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: 363960
CAS号: 128-62-1
MDL号: MFCD00069316
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说明

一般描述

(S,R)-Noscapine is a phthalideisoquinoline alkaloid found in opium. It is an antimicrotubule agent that also shows potent antitumor activity.[1]
 

应用

Noscapine may be used as a source to synthesize its bromo-derivatives, which has higher tubulin binding activity when compared to noscapine.[1] Its 3,4,5-trimethoxybenzyl analog is a potential antitumor agent.[2]
 
 

属性

质量水平

100

检测方案

97%

形式

solid

旋光性

[α]20/D −200°, c = 1 in chloroform

mp

174-176 °C (lit.)

SMILES string

COc1ccc2C(OC(=O)c2c1OC)C3N(C)CCc4cc5OCOc5c(OC)c34

InChI

1S/C22H23NO7/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18/h5-6,9,17-18H,7-8,10H2,1-4H3/t17-,18+/m1/s1

InChI key

AKNNEGZIBPJZJG-MSOLQXFVSA-N

 

安全信息

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302 - H336

预防措施声明

P301 + P312 + P330

危险分类

Acute Tox. 4 Oral - STOT SE 3

靶器官

Central nervous system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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