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蜕皮激素,20-Hydroxyecdysone;≥93% (HPLC), powder

别名:20-羟基蜕皮激素;昆虫蜕皮激素;β-蜕皮激素;多莨菪碱A;Ecdysterone, Insect moulting hormone, β-Ecdysone, 2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one, Polypodine A

Empirical Formula (Hill Notation): C27H44O7 CAS号: 5289-74-7 分子量: 480.63 Beilstein: 1917578 MDL编号: MFCD00036740 PubChem化学物质编号: 24895674 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): H5142
CAS号: 5289-74-7
MDL号: MFCD00036740
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说明

20-Hydroxyecdysone是一种蜕皮激素,通过控制涉及蜕皮和变态的基因表达,在昆虫发育、细胞增殖、生长和凋亡中发挥关键作用。 它通过包含蜕皮激素受体和超气门蛋白 (USP) 的异二聚体受体发挥作用。

应用

20-Hydroxyecdysone has been used:
  • in Leibovitz′s dissecting medium for culturing sorting zone and neuropil-associated glia and antennal lobes of Manduca sexta
  • in Schneider′s medium to reproduce ex-vivo imaginal disc eversion
  • as a supplement in Mcl8 medium for culturing Drosophila wing imaginal discs
 

生化/生理作用

20-Hydroxyecdysone is an ecdysteroid hormone that plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in molting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP).
 
 

属性

质量水平

100

无菌性

non-sterile

测定

≥93% (HPLC)

形式

powder

颜色

white to off-white

溶解性

alcohol: soluble

application(s)

agriculture
environmental

运输

ambient

储存温度

−20°C

SMILES string

[H][C@]12CC[C@]3(C)[C@H](CC[C@@]3(O)C1=CC(=O)[C@]4([H])C[C@@H](O)[C@@H](O)C[C@]24C)[C@@](C)(O)[C@H](O)CCC(C)(C)O

InChI

1S/C27H44O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19-22,29-34H,6-11,13-14H2,1-5H3/t15-,17-,19+,20-,21-,22+,24+,25+,26+,27+/m0/s1

InChI key

NKDFYOWSKOHCCO-YPVLXUMRSA-N

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 2

个人防护装备

Eyeshields, Gloves, type N95 (US)

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 55 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 8 | 香港与北京 ≥ 10
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