苦马豆素，Swainsonine；from Metarrhizium anisopliae, ≥98% (TLC)

别名：苦马豆碱；(1S,2R,8R,8aR)-1,2,8-八氢吲哚啶三醇；(1S,2R,8R,8aR)-1,2,8-Octahydroindolizidinetriol

Empirical Formula (Hill Notation): C8H15NO3 CAS号: 72741-87-8 分子量: 173.21 Beilstein: 4175740 MDL编号: MFCD00017554 PubChem化学物质编号: 24899779 NACRES: NA.85

制造商品牌: 西格玛 Sigma-Aldrich

货号（SKU）: S8195

CAS号: 72741-87-8

MDL号: MFCD00017554

签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √

目录价.SKU-Variant

1mg
5mg [+¥9,247.59]

¥4,353.16

数量:

说明

苦马豆素是一种有效的α-甘露糖苷酶抑制剂。它还具有抗转移、抗增殖和免疫调节活性。它还抑制糖蛋白加工。

应用

Swainsonine is an indolizidine alkaloid from the plant Metarrhizium anisopliae that is used as a potent α-mannosidase inhibitor. Product S8195 has been used in chemical inhibition assays of CHO Lec2 cells to inhibit glycosylation .

苦马豆素是各种α-甘露糖苷酶的有效抑制剂，特别是α-甘露糖苷酶II。它能够抑制糖蛋白加工，也可作为免疫调节剂。

生化/生理作用

Swainsonine is a potent α-mannosidase inhibitor. It also has antimetastatic, antiproliferative, and immunomodulatory activity . It also inhibits glycoprotein processing.

制备说明

Soluble in water, methanol, DMSO

其他说明

Keep container tightly closed in a dry and well-ventilated place.

属性

生物来源

Metarrhizium anisopliae

质量水平

200

测定

≥98% (TLC)

形式

lyophilized powder

储存条件

(Keep container tightly closed in a dry and well-ventilated place.)

颜色

white to faint yellow

溶解性

H₂O: soluble 1 mg/mL

抗生素抗菌谱

neoplastics

作用机制

enzyme | inhibits

储存温度

2-8°C

SMILES string

O[C@@H]1CCCN2C[C@@H](O)[C@@H](O)C12

InChI

1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6-,7?,8-/m1/s1

InChI key

FXUAIOOAOAVCGD-DCDLSZRSSA-N

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

商品规格

属性名称	属性值
储存温度 Storage temp.	2-8°C冷藏
全球实时库存 Availability √	美国St. Louis ≥ 30 \| 欧洲Eur. ≥ 10 \| 東京Tokyo ≥ 9 \| 香港与北京 ≥ 30

商品标签 [tags]

苦马豆素 (2)