芬戈莫德盐酸盐，FTY720； certified reference material, pharmaceutical secondary standard

图片 芬戈莫德盐酸盐，FTY720； certified reference material, pharmaceutical secondary standard
别名：盐酸芬戈莫德标准品；2-氨基-2- 2-（4-辛基-苯基）-乙基-丙烷-1,3-二醇 盐酸盐；2-Amino-2-2-(4-octyl-phenyl)-ethyl-propane-1,3-diol hydrochloride, Fingolimod hydrochloride

Empirical Formula (Hill Notation): C19H33NO2 · HCl CAS号: 162359-56-0 分子量: 343.93
制造商品牌: 色谱科 Supelco , 西格玛 Sigma-Aldrich
货号（SKU）: PHR2790
CAS号: 162359-56-0
MDL号: MFCD00939512
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √
¥11,997.12

说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
 

生化/生理作用

FTY720是一种免疫调节药物以及1-磷酸鞘氨醇（S1P）受体的调节剂。 鞘氨醇激酶对FTY270的磷酸化可导致S1P1R的内化，从而螯合淋巴结中的淋巴细胞，阻止它们参与自身免疫反应。 临床上，它已被批准用于治疗多发性硬化症（MS）。研究显示其可通过抑制S1PR阻断和逆转紫杉醇诱导的化疗诱导的周围神经病变（CIPN），并可抑制小鼠脑海马中组蛋白脱乙酰酶的活性，从而调节记忆。
 

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
 

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
 

附注

To see an example of a Certificate of Analysis for this material enter LRAC6340 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
 
 

属性

等级

certified reference material
pharmaceutical secondary standard

Agency

traceable to Ph. Eur. Y0002055
traceable to USP 1270480

描述

Pharmaceutical Secondary Standard; Certified Reference Material

API family

fingolimod

形式

powder

包装

pkg of 500 mg

储存温度

2-30°C

InChI

1S/C19H33NO2.ClH/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20,15-21)16-22;/h9-12,21-22H,2-8,13-16,20H2,1H3;1H

InChI key

SWZTYAVBMYWFGS-UHFFFAOYSA-N

 

安全信息

象形图

Health hazard
GHS08

警示用语：

Warning

危险声明

H373

预防措施声明

P260 - P314 - P501

危险分类

STOT RE 2

靶器官

Immune system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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