芋螺睡眠肽G，Conantokin G；≥95% (HPLC)

别名：Conantokin G, Gly-Glu-γ-CarboxyGlu-γ-CarboxyGlu-Leu-Gln-γ-CarboxyGlu-Asn-Gln-γ-CarboxyGlu-Leu-Ile-Arg-γ-CarboxyGlu-Lys-Ser-Asn-NH2

CAS号: 93438-65-4 MDL编号: MFCD00214606

制造商品牌: 西格玛 Sigma-Aldrich

货号（SKU）: 5.04480

CAS号: 93438-65-4

MDL号: MFCD00214606

签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √

目录规格.SKU-Variant

说明

一般描述

The most selective and potent non-competitive antagonist among the members of the conantokin peptide family for NR2B-containing NMDAR channels (K_i = 0.8 µM with close to 100% inhibition of NR1/NR2B mediated current). Widely used for studies related to NMDAR neurotransmissions in both peripheral and center nervous systems.

生化/生理作用

Primary Target
NMDA receptors

包装

Yes

警告

Toxicity: Standard Handling (A)

序列

Gly-Glu-γ-CarboxyGlu-γ-CarboxyGlu-Leu-Gln-γ-CarboxyGlu-Asn-Gln-γ-CarboxyGlu-Leu-Ile-Arg-γ-CarboxyGlu-Lys-Ser-Asn-NH₂

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Sheng, Z., et al. 2007. Neuropharmacology.53, 145.
Sheng, Z., et al. 2009. Neuropharmacology.57, 127.
Zhou, L., et al. 1996. J. Neurochemistry.66, 620.
Hammerland, L., et al. 1992. Eur. J. Pharmacol.226, 239.

Mena, E., et al. 1990. Neurosci Lett.118, 241.
Donevan, D., et al. 2000. Mol Pharmacol.58, 614.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

属性

检测方案

≥95% (HPLC)

质量水平

100

形式

powder

效能

0.8 μM K_i

制造商/商品名称

Calbiochem^®

储存条件

OK to freeze
protect from light

颜色

white

溶解性

water: 1 mg/mL

储存温度

−20°C

InChI

1S/C88H138N26O44/c1-7-34(6)61(77(138)103-41(12-10-20-98-88(96)97)63(124)107-48(23-35(78(139)140)79(141)142)69(130)100-40(11-8-9-19-89)64(125)113-54(31-115)76(137)104-45(62(95)123)28-57(93)118)114-75(136)47(22-33(4)5)106-70(131)49(24-36(80(143)144)81(145)146)109-67(128)44(14-17-56(92)117)102-74(135)53(29-58(94)119)112-73(134)51(26-38(84(151)152)85(153)154)110-66(127)43(13-16-55(91)116)101-68(129)46(21-32(2)3)105-71(132)52(27-39(86(155)156)87(157)158)111-72(133)50(25-37(82(147)148)83(149)150)108-65(126)42(15-18-60(121)122)99-59(120)30-90/h32-54,61,115H,7-31,89-90H2,1-6H3,(H2,91,116)(H2,92,117)(H2,93,118)(H2,94,119)(H2,95,123)(H,99,120)(H,100,130)(H,101,129)(H,102,135)(H,103,138)(H,104,137)(H,105,132)(H,106,131)(H,107,124)(H,108,126)(H,109,128)(H,110,127)(H,111,133)(H,112,134)(H,113,125)(H,114,136)(H,121,122)(H,139,140)(H,141,142)(H,143,144)(H,145,146)(H,147,148)(H,149,150)(H,151,152)(H,153,154)(H,155,156)(H,157,158)(H4,96,97,98)

InChI key

HTBKFGWATIYCSF-UHFFFAOYSA-N

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格

属性名称	属性值
储存温度 Storage temp.	-20°C低温冷冻
全球实时库存 Availability √	美国St. Louis ≥ 20 \| 欧洲Eur. ≥ 16 \| 東京Tokyo ≥ 5 \| 香港与北京 ≥ 20

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