胰蛋白酶抑制剂来源于鸡蛋白 [胰酶抑制剂]，Trypsin inhibitor from chicken egg white；Type III-O (free of ovoinhibitor)

General description

卵类粘蛋白或胰蛋白酶抑制剂是大多数禽蛋白中富含的蛋白质。鸡蛋白约由186个氨基酸残基组成，且高度糖基化。三个串联的结构域均与胰蛋白酶抑制剂同源。其免疫原性很高，而且可能是大多数鸡蛋过敏的原因。

Application

Trypsin inhibitor from chicken egg white has been used:
• to terminate proteolysis reaction^[2]
• in OVO-1 solution to triturate the cell suspension for the dissociation of retina^[4]
• in phosphate buffered saline for dissociation of cortices^[3]

包装

1, 5 g in poly bottle

250, 500 mg in poly bottle

Biochem/physiol Actions

Ovomucoid possesses trypsin inhibitor activity. It has several conformational and linear epitopes that can be bound by immunoglobulin E (IgE). It is highly stable against heat and proteolysis.^[1]

Unit Definition

一个胰蛋白酶单位将在pH 7.6，25℃，反应体积 3.2 mL，1 cm 光路条件下，每分钟产生0.001 以 BAEE 为底物的 δA ₂₅₃ 。

Other Notes

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性质

安全信息