胡黄连苷II，Picroside II；≥98% (HPLC)

图片 胡黄连苷II，Picroside II；≥98% (HPLC)
别名：(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-六氢-6-[(4-羟基-3-甲氧基苯甲酰基)氧基]-1a-羟甲基环氧代[4,5]环戊[1,2-c]吡喃-2-基-β-D-吡喃葡萄糖苷；6-香草基二氧化铝苷；香草酰二氢吡咯烷酮；(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranoside, 6-Vanillylcatalpol, Amphicoside II, Vanilloyl catalpol

Empirical Formula (Hill Notation): C23H28O13 CAS号: 39012-20-9 分子量: 512.46 EC 号: 254-247-6 NACRES: NA.25
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: G0174
CAS号: 39012-20-9
MDL号: MFCD00135962
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说明

一般描述

PicrosideII (PII) is a monoterpene, iridoid glycoside, and one of the main bioactivecompounds sourced from Picrorhiza kurroa.
 

应用

PicrosideII has been used as a reference standard to analyze and validate picroside-II from Picrorhiza kurroa using high-performance liquid chromatography (HPLC).
 

生化/生理作用

Picroside II displaysmany anti-cancer properties such as anti-metastatic, anti-angiogenic, and anti-apoptotic activities in both in vitro and in vivo studies.It also exerts antioxidant, anti-inflammatory, and antidiarrheal effectsagainst acute oxidative injuries such as severe acute pancreatitis-inducedintestinal barrier injury. PII has protective effects onischemia/reperfusion (I/R)-induced injury by interacting with differentmechanisms in various in vitro and in vivo models.
Phytochemical found in Traditional Chinese Medicine herbal preparations. Picroside II, a glucoside, is reported to have hepatoprotective, cardioprotective, and neuroprotective properties.
 
 

属性

检测方案

≥98% (HPLC)

质量水平

100

溶解性

ethanol: 1 mg/mL, clear, colorless

储存温度

2-8°C

SMILES string

OC1[C@@H](O)[C@H](O)C(CO)O[C@H]1O[C@@H]2OC=C[C@]3([H])[C@@]2([H])[C@](O4)(CO)[C@@H]4[C@H]3OC(C5=CC=C(O)C(OC)=C5)=O

InChI

1S/C23H28O13/c1-31-12-6-9(2-3-11(12)26)20(30)34-18-10-4-5-32-21(14(10)23(8-25)19(18)36-23)35-22-17(29)16(28)15(27)13(7-24)33-22/h2-6,10,13-19,21-22,24-29H,7-8H2,1H3

InChI key

AKNILCMFRRDTEY-UHFFFAOYSA-N

 

安全信息

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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