sevenspikes.themes.common.filters
sevenspikes.themes.common.closemenu

胆钙化醇 [维生素D3],Cholecalciferol;meets USP testing specifications, 97.0-103.0%

别名:胆骨化醇;(+)-维生素D3;活化7-脱氢胆固醇;活化7-脱氢胆甾醇;9,10-开环胆甾-5,7,10(19)-三烯-3beta-醇;(+)-Vitamin D3;7-Dehydrocholesterol activated;Activated 7-dehydrocholesterol;Calciol

CAS号 67-97-0 经验分子式(希尔表示法) C27H44O 分子量 384.64 Beilstein/REAXYS Number 2339331 EINECS 编号 200-673-2 MDL number MFCD00078131 eCl@ss 34058003 PubChem Substance ID 24892404 NACRES NA.21
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): C1357
CAS号: 67-97-0
MDL号: MFCD00078131
增值税发票 √ 免费送货 √ 订货电话:010-68689484
¥457.32

产品描述

General description

Cholecalciferol (vitamin D3), a fat-soluble steroid is produced in the skin.[1]

Application

Cholecalciferol has been used:
• to induce arterial medial calcification (AMC) in mice[2]
• to study its impact in vascular remodeling associated with vascular calcification (VC) in murine model of obesity and insulin resistance (ob/ob mice)[3]
• to study its effect on anchorage dependent growth of RWPE2-W99 cells in monolayer culture[4]

包装

1 g in ampule

25 g in glass bottle

250 mg in ampule

Biochem/physiol Actions

维生素 D 借以发挥作用的受体是配体依赖性转录因子超家族的成员。调控正常细胞和癌细胞的增殖和分化。对乳腺癌、结肠癌和前列腺癌细胞具有抗增殖和抗转移作用。肠和骨骼中的活化维生素 D 受体维持着钙的吸收和平衡。

性质

Agency/Methodmeets USP testing specifications
Quality Level200
assay97.0-103.0%
formcrystalline
colorwhite
mp83-86 °C (lit.)
Featured IndustryPharmaceutical (small molecule)
storage temp.2-8°C
SMILES stringCC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C
InChI1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1
InChI keyQYSXJUFSXHHAJI-YRZJJWOYSA-N
Gene Informationhuman ... VDR(7421)


安全信息

符号
信号词 Danger
危害码 (欧洲) T+
风险声明 (欧洲) 24/25-26-48/25
安全声明 (欧洲) 28-36/37-45
RIDADR UN 2811 6.1 / PGII
WGK德国 WGK 2
RTECS VS2900000
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 155 | 欧洲Eur. ≥ 66 | 東京Tokyo ≥ 78 | 香港与北京 ≥ 32