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胆酸钠水合物 [水合胆酸钠],Sodium cholate hydrate;suitable for cell culture, BioReagent, ≥99.0% (HPLC)

别名:3α,7α,12α-三羟基-5β-胆甾烷-24-羧酸钠盐;胆酸钠盐;3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt, Cholalic acid sodium salt

CAS号 206986-87-0 经验分子式(希尔表示法) C24H39NaO5 · xH2O 分子量 430.55 (anhydrous basis) Beilstein/REAXYS Number 3582354 EINECS 编号 206-643-5 MDL number MFCD00150749 PubChem Substance ID 24893147 NACRES NA.75
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): C9282
CAS号: 206986-87-0
MDL号: MFCD00150749
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$164.24

产品描述

General description

Cholate is a primary bile acid[3] produced from cholesterol in the liver.[5] It is an anionic detergent synthesized from cholesterol in the presence of sterol 12α-hydroxylase (CYP8B1).[1]

Application

Sodium cholate hydrate has been used:
• as a bile acid to induce bile acid-responsive (BEAR) transcription system[2],
• as a component of Campylobacter defined broth (CDB) to test its effect on stress response in Campylobacter jejuni{52
• to test its sensitivity towards the bile acid sensor[4]

用于提取膜蛋白的非变性洗涤剂。

包装

25, 100 g in poly bottle

Biochem/physiol Actions

Reduction in 12-α hydroxylase activity leads to low levels of cholic acid in liver disease.[5]

性质

Quality Level200
biological sourcebovine bile
ovine bile
descriptionanionic
product lineBioReagent
assay≥99.0% (HPLC)
formpowder
mol wtmicellar avg mol wt 900-1300
aggregation number2-3
application(s)cell culture | mammalian: suitable
CMC9-15 mM (20-25°C)
solubilitywater: 100 mg/mL, clear, colorless to light yellow
HLB18
SMILES stringO.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C
InChI1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1
InChI keyMUVVIYFKOVLQHL-RCVKHMDESA-M


安全信息

个人防护装备 EyeshieldsGlovestype N95 (US)
RIDADR NONH for all modes of transport
WGK德国 WGK 3
商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 99 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 22 | 香港与北京 ≥ 32
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