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胆酸钠水合物 [水合胆酸钠]，Sodium cholate hydrate；suitable for cell culture, BioReagent, ≥99.0% (HPLC)

别名：3α,7α,12α-三羟基-5β-胆甾烷-24-羧酸钠盐；胆酸钠盐；3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt, Cholalic acid sodium salt

CAS号 206986-87-0 经验分子式（希尔表示法） C24H39NaO5 · xH2O 分子量 430.55 (anhydrous basis) Beilstein/REAXYS Number 3582354 EINECS 编号 206-643-5 MDL number MFCD00150749 PubChem Substance ID 24893147 NACRES NA.75

制造商品牌: 西格玛 Sigma-Aldrich

货号（SKU）: C9282

CAS号: 206986-87-0

MDL号: MFCD00150749

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目录价.SKU-Variant

25g
100g [+¥1,342.85]

¥817.94

数量:

产品描述

General description

Cholate is a primary bile acid^[3] produced from cholesterol in the liver.^[5] It is an anionic detergent synthesized from cholesterol in the presence of sterol 12α-hydroxylase (CYP8B1).^[1]

Application

Sodium cholate hydrate has been used:
• as a bile acid to induce bile acid-responsive (BEAR) transcription system^[2],
• as a component of Campylobacter defined broth (CDB) to test its effect on stress response in Campylobacter jejuni{52
• to test its sensitivity towards the bile acid sensor^[4]

用于提取膜蛋白的非变性洗涤剂。

包装

25, 100 g in poly bottle

Biochem/physiol Actions

Reduction in 12-α hydroxylase activity leads to low levels of cholic acid in liver disease.^[5]

性质

Quality Level	200
biological source	bovine bile
	ovine bile
description	anionic
product line	BioReagent
assay	≥99.0% (HPLC)
form	powder
mol wt	micellar avg mol wt 900-1300
aggregation number	2-3
application(s)	cell culture \| mammalian: suitable
CMC	9-15 mM (20-25°C)
solubility	water: 100 mg/mL, clear, colorless to light yellow
HLB	18
SMILES string	O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C
InChI	1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1
InChI key	MUVVIYFKOVLQHL-RCVKHMDESA-M

安全信息

个人防护装备 Eyeshields, Gloves, type N95 (US)

RIDADR NONH for all modes of transport

WGK德国 WGK 3

商品规格

属性名称	属性值
储存温度 Storage temp.	常温阴凉避光
全球实时库存 Availability √	美国St. Louis ≥ 190 \| 欧洲Eur. ≥ 66 \| 東京Tokyo ≥ 82 \| 香港与北京 ≥ 55

商品标签

水合胆酸钠 (5)

胆酸钠水合物 [水合胆酸钠]，Sodium cholate hydrate；suitable for cell culture, BioReagent, ≥99.0% (HPLC)

产品描述

General description

Application

包装

Biochem/physiol Actions

性质

安全信息

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