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维生素B12 [氰钴胺素],Vitamin B12 [Cyanocobalamin];tested according to Ph. Eur., 96.0-102.0% dry basis

别名:氰基钴胺素;氰钴胺;CN-Cbl;动物蛋白因子;抗恶性贫血维生素;维生素乙B12;维他命B12;α-(5,6-Dimethylbenzimidazolyl)cyanocobamide;Cyanocob(III)alamin;Cyanocobalamin

CAS号 68-19-9 经验分子式(希尔表示法) C63H88CoN14O14P 分子量 1355.37 Beilstein/REAXYS Number 4122889 EINECS 编号 200-680-0 PubChem Substance ID 329756307 NACRES NA.21
货号(SKU): 43107
CAS号: 68-19-9
MDL号: MFCD00151092
增值税发票 √ 免费货运 [顺丰 联邦] √
¥11,704.33

产品描述

General description

Cyanocobalamin, also referred to as Vitamin B12, is a water soluble vitamin.[4]

Application

Cyanocobalamin was added in the assay buffer during the analysis step of ELISA for ensuring that all transcobalamin was saturated with cobalamin before analysis.[1] Cyanocobalamin was also used for examining its impact on the expression of mPer1 and mPer2 in vivo.[2]

Biochem/physiol Actions

Cyanocobalamin plays a role in functioning of brain and nervous system. It is also involved in hematopoiesis. Vitamin B12 deficiency leads to megaloblastic anemia. It is also associated with irreversible nervous system breakdown leading to spinal cord degeneration.[4]

Cyanocobalamin refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. Cyanocobalamin along with other B vitamins thiamine (B1) and pyridoxine (B6) blocks the thermal hyperalgesia in rats with neuropathic pain caused by spinal ganglia compression (CCD) or loose ligation of the sciatic nerve (CCI).[3] It can stimulate the anaerobic biodegradation of chloroform.

性质

Quality Level100
biological sourcefermentation/recombinant
Agency/Methodtested according to Ph. Eur.
assay96.0-102.0% dry basis
formpowder
application(s)cell analysis: suitable
colordark red
solubilitywater: soluble 1 gm in 80 ml
acetone: insoluble
alcohol: soluble
chloroform: insoluble
diethyl ether: insoluble
storage temp.2-8°C
SMILES stringC/C(C1=N[C@]([C@]([C@H](CC(N)=O)[C@@]/2(C)CCC(NC[C@@H](OP([O-])(O[C@H]3[C@@H](O)[C@@H](N4C=[N]5C6=C4C=C(C)C(C)=C6)O[C@@H]3CO)=O)C)=O)([H])N([Co+]5C#N)C2=C(C)/C([C@@H](CCC(N)=O)C/7(C)C)=NC7=C/8)(C)[C@@](C)(CC(N)=O)[C@@H]1CCC(N)=O)=C9N=C8[C@@H](CCC(N)=O)[C@
InChI1S/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;;+2/p-2/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57?,59-,60+,61+,62+;;/m1../s1
InChI keyRMRCNWBMXRMIRW-QJRSUKKJSA-L


安全信息

个人防护装备 EyeshieldsGlovestype N95 (US)
RIDADR NONH for all modes of transport
WGK德国 WGK 1
RTECS GG3750000
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 88 | 欧洲Eur. ≥ 126 | 東京Tokyo ≥ 46 | 香港与北京 ≥ 62
商品标签