细胞色素C来源于牛心脏，Cytochrome c from bovine heart；≥95% based on Mol. Wt. 12,327 basis

Application

Cytochrome c has been identified as an important mediator in apoptotic pathways. The release of mitochondrial cytochrome c into the cytoplasm stimulates apoptosis and is commonly used as an indicator of the apoptotic process in the cell. Investigation on the effect of Paris Saponin I (PS I) on human gastric carcinoma cell growth (SGC7901 cells) have shown an elevated level cytoplasmic cytochrome c. Results are an inhibition of proliferation in SGC7901 cells by inducing mitochondria-dependent apoptosis through cytochrome c.

包装

1 g in poly bottle

10, 50, 100, 250 mg in poly bottle

Biochem/physiol Actions

细胞色素c可在亚铁态和三价铁态之间迅速转化，这使其成为有效的生物电子载体。它在动植物的细胞氧化过程中发挥重要作用。通常视作是呼吸链中的通用连接，它在可呼吸底物与氧气之间形成必要的电子桥。

Preparation Note

Prepared with acetic acid without using TCA.

Other Notes

想要了解更多细胞色素c和电子传递的信息，请访问www.sigma-aldrich.com/enzymeexplorer.

性质

安全信息