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细胞色素C来源于牛心脏,Cytochrome c from bovine heart;≥95% based on Mol. Wt. 12,327 basis

CAS号 9007-43-6 EINECS 编号 232-700-9 MDL number MFCD00130890 NACRES NA.61
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): C3131
CAS号: 9007-43-6
MDL号: MFCD00130890
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产品描述

Application

Cytochrome c has been identified as an important mediator in apoptotic pathways. The release of mitochondrial cytochrome c into the cytoplasm stimulates apoptosis and is commonly used as an indicator of the apoptotic process in the cell. Investigation on the effect of Paris Saponin I (PS I) on human gastric carcinoma cell growth (SGC7901 cells) have shown an elevated level cytoplasmic cytochrome c. Results are an inhibition of proliferation in SGC7901 cells by inducing mitochondria-dependent apoptosis through cytochrome c.

包装

1 g in poly bottle

10, 50, 100, 250 mg in poly bottle

Biochem/physiol Actions

细胞色素c可在亚铁态和三价铁态之间迅速转化,这使其成为有效的生物电子载体。它在动植物的细胞氧化过程中发挥重要作用。通常视作是呼吸链中的通用连接,它在可呼吸底物与氧气之间形成必要的电子桥。

Preparation Note

Prepared with acetic acid without using TCA.

Other Notes

想要了解更多细胞色素c电子传递的信息,请访问www.sigma-aldrich.com/enzymeexplorer.

性质

Quality Level200
biological sourcebovine heart
assay≥95% based on Mol. Wt. 12,327 basis
formpowder
mol wt12327 Da
application(s)cell culture | mammalian: suitable
storage temp.−20°C
Gene Informationcow ... CYC1(512500)


安全信息

个人防护装备 EyeshieldsGlovestype N95 (US)
RIDADR NONH for all modes of transport
WGK德国 WGK 3
RTECS HA5365000
商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 55 | 欧洲Eur. ≥ 128 | 東京Tokyo ≥ 44 | 香港与北京 ≥ 16
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