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神经降压素,Neurotensin;Potent hypothalamic peptide neurotransmitter.,≥97% (HPLC)

别名:一种有效的下丘脑肽神经递质。Neurotensin, Pyr-LYENKPRRPYIL; Empirical Formula (Hill Notation): C78H121N21O20 CAS号: 39379-15-2 分子量: 1672.92
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): 05-23-1200
CAS号: 39379-15-2
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √
¥2,960.00

说明

一种有效的下丘脑肽神经递质。一种内源性抗精神病化合物,可降低血压,增加血管通透性,并增加大鼠胰高血糖素,葡萄糖,生长激素和催乳素的血浆水平。去甲肾上腺素能活性的调节剂。异质地分布在哺乳动物中枢神经系统中,并具有许多神经递质样特征。
作为有效的下丘脑肽神经递质。可降低血压,增加血管通透性,增加大鼠胰高血糖素,葡萄糖,生长激素和催乳素的血浆水平。去甲肾上腺素能活性的调节剂。异质地分布在哺乳动物中枢神经系统中,并具有许多神经递质样特征。

一般描述

Potent hypothalamic peptide neurotransmitter. An endogenous anti-psychotic compound that lowers blood pressure, increases vascular permeability, and increases plasma levels of glucagon, glucose, growth hormone and prolactin in rats. A modulator of noradrenergic activity. Heterogeneously distributed in the mammalian central nervous system and has many neurotransmitter-like characteristics.
Potent hypothalamic peptide neurotransmitter. Lowers blood pressure, increases vascular permeability and increases plasma levels of glucagon, glucose, growth hormone and prolactin in rats. A modulator of noradrenergic activity. Heterogeneously distributed in the mammalian central nervous system and has many neurotransmitter-like characteristics.
 

生化/生理作用

Cell permeable: no
Primary Target
Modulator of noradrenergic activity
Product does not compete with ATP.
Reversible: no
 

包装

Yes
 

警告

Toxicity: Standard Handling (A)
 

序列

Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH
 

其他说明

Kinkead, B., et al. 1999. Biol. Psychiatr.46, 340.
Tyler, B.M., et al. 1998. Brain Res. 792, 246.
Tsuda, K., and Masuyuma, Y. 1993. Am. J. Hypertens. 6, 473.
 

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
 
 

属性

质量水平

测定

≥97% (HPLC)

形式

lyophilized solid

manufacturer/tradename

Calbiochem®

储存条件

OK to freeze
desiccated (hygroscopic)

颜色

white to off-white

溶解性

5% acetic acid: 1 mg/mL

运输

ambient

储存温度

−20°C

InChI

1S/C78H121N21O20/c1-7-43(6)63(73(115)96-57(76(118)119)37-42(4)5)97-70(112)55(39-45-21-25-47(101)26-22-45)95-72(114)59-18-13-35-99(59)75(117)52(16-11-33-86-78(83)84)90-64(106)48(15-10-32-85-77(81)82)89-71(113)58-17-12-34-98(58)74(116)51(14-8-9-31-79)91-69(111)56(40-60(80)102)94-66(108)50(28-30-62(104)105)88-68(110)54(38-44-19-23-46(100)24-20-44)93-67(109)53(36-41(2)3)92-65(107)49-27-29-61(103)87-49/h19-26,41-43,48-59,63,100-101H,7-18,27-40,79H2,1-6H3,(H2,80,102)(H,87,103)(H,88,110)(H,89,113)(H,90,106)(H,91,111)(H,92,107)(H,93,109)(H,94,108)(H,95,114)(H,96,115)(H,97,112)(H,104,105)(H,118,119)(H4,81,82,85)(H4,83,84,86)

InChI key

PCJGZPGTCUMMOT-UHFFFAOYSA-N

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 50 | 欧洲Eur. ≥ 12 | 東京Tokyo ≥ 20 | 香港与北京 ≥ 50