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磺胺对甲氧嘧啶,Sulfameter;powder

别名:胺-5-甲氧嘧啶;5-甲氧基磺胺嘧啶;N1-(5-甲氧基嘧啶-2-基)磺胺;5-Methoxysulfadiazine, N1-(5-Methoxypyrimidin-2-yl)sulfanilamide, Sulfamethoxydiazine

Empirical Formula (Hill Notation): C11H12N4O3S CAS号: 651-06-9 分子量: 280.30 Beilstein: 621130 EC 号: 211-480-8 MDL编号: MFCD00006067 PubChem化学物质编号: 24899422 NACRES: NA.85
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): S0383
CAS号: 651-06-9
MDL号: MFCD00006067
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √
¥995.18

说明

化学结构:磺酰胺
磺胺是一种磺胺类抗生素,用作麻风治疗剂和治疗尿路感染。它已被研究为妊娠期抗氯喹疟疾的潜在治疗方法。
磺胺是一种磺胺类抗生素。磺胺类药物通过抑制二氢叶酸合酶来阻断二氢叶酸的合成。磺胺是细菌对氨基苯甲酸(PABA)的竞争性抑制剂,这是细菌合成叶酸所必需的。磺胺美特是一种二氢叶酸还原酶(DHFR)抑制剂。磺胺类药物对革兰氏阳性菌和革兰氏阴性菌具有活性。抗性模式是通过改变二氢叶酸合酶或叶酸合成的替代途径。

一般描述

Chemical structure: sulfonamide
 

应用

Sulfameter is a sulfonamide antibiotic used as a leprostatic agent and to treat urinary tract infections. It has been investigated as a potential therapy for chloroquine-resistant malaria during pregnancy.
 

生化/生理作用

Sulfameter is a sulfonamide antibiotic. Sulfonamides block the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfonamides are competitive inhibitors of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. Sulfameter is a dihydrofolate reductase (DHFR) inhibitor. Sulfonamides are active against Gram positive bacteria and Gram negative bacteria. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.
 

其他说明

Keep container tightly closed in a dry and well-ventilated place. Light sensitive.
 
 

属性

形式

powder

质量水平

200

储存条件

(Keep container tightly closed in a dry and well-ventilated place. Light sensitive.)

颜色

white to faint yellow

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria
mycobacteria
parasites

作用机制

enzyme | inhibits

储存温度

2-8°C

SMILES string

COc1cnc(NS(=O)(=O)c2ccc(N)cc2)nc1

InChI

1S/C11H12N4O3S/c1-18-9-6-13-11(14-7-9)15-19(16,17)10-4-2-8(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)

InChI key

GPTONYMQFTZPKC-UHFFFAOYSA-N

 

安全信息

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 2

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 30 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 30
商品标签 [tags]