磷酸葡萄糖变位酶来源于兔肌肉，Phosphoglucomutase from rabbit muscle [PGM]；≥100 units/mg protein

图片 磷酸葡萄糖变位酶来源于兔肌肉，Phosphoglucomutase from rabbit muscle [PGM]；≥100 units/mg protein
别名：α-D-葡萄糖-1,6-二磷酸酶, α-D-葡萄糖磷酸转移酶，α-D-Glucose-1,6-bisphosphatase, α-D-Glucose-1-phosphate phosphotransferase

CAS号: 9001-81-4 EC 号: 5.4.2.2 (BRENDA, IUBMB) MDL编号: MFCD00131886
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: SRE0069
CAS号: 9001-81-4
MDL号: MFCD00131886
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说明

一般描述

The phosphoglucomutase (PGM) molecule, a single polypeptide chain, is made up of four α/β domains. The domains form a compact heart-shaped structure with a large fissure between the two lobes, and the molecule comprises about 40 secondary structural components. The active enzymatic site of the molecule is located at the bottom of the crevice on the surface of domain I. Rabbit muscle phosphoglucomutase (RB-PGM) is a monomer with unique four-domain architecture.[1]
 

应用

Phosphoglucomutase from rabbit muscle may be used in dephosphorylation to investigate the hexose bisphosphate activation of phosphoglucomutase.[1]
 

生化/生理作用

Phosphoglucomutase (PGM) mainly catalyzes the interconversion of glucose 1-phosphate and glucose 6-phosphate via a glucose 1,6-diphosphate intermediate. Hence it plays a key role in glycolysis and gluconeogenesis.[1]
 

单位定义

One unit will convert 1.0 μmole of α-D-glucose 1-phosphate to α-D-glucose 6-phosphate per min at pH 7.4 at 30 °C.
 

外形

Lyophilized powder containing Tris HCl, EDTA, magnesium acetate and carbohydrate
 
 

属性

形式

lyophilized powder

质量水平

200

specific activity

≥100 units/mg protein

异质活性

Lactic dehydroenase ≤0.5%
Phosphoglucose Isomerase ≤0.01%
pyruvate kinase ≤0.05%

运输

wet ice

储存温度

−20°C

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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