General description
Protamine are proteins rich in cysteine and arginine.[4] It possesses many phosphorylation sites.[5] It is found to be localized to the sperm head.[6]
Application
Protamine sulfate salt from salmon has been used:
• in the pretreament of cells to study its effect on respiratory syncytial virus infection[1]
• in lentivirus production[2]
• to derivatize it into a diazeniumdiolate NO donor[3]
与由Esterquat-1组成的具有可比性的固体脂质纳米颗粒(SLN)相比,SLN形式的鱼精蛋白可更有效地促进质粒DNA的转染,而且细胞毒性更低。可用于从蛋白样品中去除DNA或用于纯化DNA结合蛋白。可用作逆转录病毒介导的基因转移中聚凝胺的替代物。
与由Esterquat-1组成的具有可比性的固体脂质纳米颗粒(SLN)相比,SLN形式的鱼精蛋白可更有效地促进质粒DNA的转染,而且细胞毒性更低。包装
1, 5, 10, 25, 100 g in poly bottle
Biochem/physiol Actions
硫酸鱼精蛋白是一种可与 DNA 结合并产生沉淀的小阳离子蛋白。它能中和肝素的抗凝血活性,还可抑制脂蛋白脂肪酶。