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硫酸葡聚糖钠盐来源于明串珠菌属,Dextran sulfate sodium salt from Leuconostoc spp.;average mol wt 9,000-20,000

CAS号: 9011-18-1 MDL编号: MFCD00081551 NACRES: NA.21
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): D6924
CAS号: 9011-18-1
MDL号: MFCD00081551
增值税发票 √ 技术支持 √ 质量保障 √ 电话:13910327035
¥1,174.56

说明

葡聚糖硫酸钠是α-1,6-D-吡喃葡萄糖的天然聚合物。它是一种亲水、可生物降解和生物相容的聚阴离子聚合物。这种高度支化的多糖具有1,6和1,4糖苷键,每个葡萄糖基单元由2.3个硫酸基组成。
硫酸葡聚糖可能具有抗凝血和抗病毒财产。它也有助于降低胆固醇水平。在医学领域,它被广泛用作血浆体积膨胀剂和纤维蛋白溶解剂。硫酸葡聚糖也可用作壳聚糖(CH)的交联剂。

一般描述

Dextran sulfate sodium is a natural polymer of α-1,6-D-glucopyranose. It is a hydrophilic, biodegradable, and biocompatible polyanionic polymer. This highly branched polysaccharide has 1,6 and 1,4 glycosidic linkages, consisting of 2.3 sulfate groups per glucosyl unit.
 

应用

Dextran sulfate sodium salt from Leuconostoc spp. has been used:
  • to evaluate the participation of sulfated glycans on the interaction of recombinant human proacrosin/acrosin with zona pellucida (ZP) glycoproteins
  • to inject into the vitreous cavity of embryonic day five chick embryos to assess the eye size and to study its impact on cell proliferation in the retina
  • to test the structural specificity of binding of TNF-stimulated gene 6 (TSG-6) to immobilized hyaluronan (HA)

生化/生理作用

Dextran sulfate may exhibit anti-coagulant and antiviral properties. It may also help to lower cholesterol levels. It is extensively used as a plasma volume expander and fibrinolytic in the medical field. Dextran sulfate can also be used as a cross-linker for chitosan (CH).
 
 

属性

生物来源

bacterial (Leuconostoc mesenteroides)

质量水平

形式

powder

旋光性

[α]/D 90 to 105 °, c = 6% (w/v)

分子量

average mol wt 9,000-20,000

组成

Sulfur Content, 16.0-19.0%

溶解性

H2O: 100 mg/mL

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 2

个人防护装备

Eyeshields, Gloves, type N95 (US)

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16
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