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硫酸庆大霉素 [正泰霉素],Gentamicin sulfate;potency: ≥590 μg Gentamicin base per mg

别名:庆大霉素硫酸酯;庆大霉素硫酸盐;庆大霉素C;庆大霉素硫酸盐;硫酸艮他霉素;硫酸正泰霉素;硫酸双生霉素;Garamycin;Gentamicin sulfate salt;Gentiomycin C

CAS号 1405-41-0 EINECS 编号 215-778-9 MDL number MFCD00270181 eCl@ss 42020823 PubChem Substance ID 329799915 NACRES NA.76
货号(SKU): G3632
CAS号: 1405-41-0
MDL号: MFCD00270181
增值税发票 √ 免费货运 [顺丰 联邦] √
¥393.00

产品描述

General description

Chemical structure: aminoglycoside

包装

1, 5, 10, 25, 100 g in glass bottle

250 mg in glass bottle

Application

Gentamicin sulfate, a broad-spectrum antibiotic, used as a selection agent (gentamicin-resistance gene) in cell culture and molecular biology applications. This product is recommended for use at 50 mg/L.

Biochem/physiol Actions

作用方式:庆大大霉素通过和30S核糖亚基结合,引起密码子误读,阻碍肽酰转移酶从供体位点转移到受体位点 庆大霉素对于Pseudomonas aeruginosa的杀菌效果是通过庆大霉素和外膜结合,取代天然阳离子,使膜不稳定,在细胞表面形成孔洞实现的。

抗微生物谱: 包括革兰氏阴性和革兰氏阳性细菌,包括对于四环素,氯霉素,卡那霉素和粘菌素,某些特定假单胞菌菌株,变形杆菌属,Staphylococcus 和Streptococcus的抗性。

Components

Freely soluble in water, practically insoluble in ethanol

Gentamicin is an aminoglycoside complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is used as the sulfate salt. There are three components, each consisting of five basic nitrogens and requiresing five equivalents of sulfuric acid per mole of gentamicin base.

Caution

Sterile solutions should be stored at 2-8°C. Solutions have also been shown to be stable at room temperature and in boiling aqueous buffers of pH 2-142.

性质

Quality Level300
biological sourceMicromonospora purpurea
formpowder
potency≥590 μg Gentamicin base per mg
concentration50 μg/mL in H2O (is the recommended working concentration for eukaryotic cell culture)
colorwhite to off-white
Mode of actionprotein synthesis | interferes
antibiotic activity spectrumGram-negative bacteria
Gram-positive bacteria
mycoplasma
storage temp.2-8°C
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InChI keyRDEIXVOBVLKYNT-HDZPSJEVSA-N


安全信息

符号
GHS07  GHS07
信号词 Warning
危害声明 H317
警示性声明 P280 - P302 + P352
危害码 (欧洲) Xn
风险声明 (欧洲) 42/43
安全声明 (欧洲) 22-36/37-45
RIDADR NONH for all modes of transport
WGK德国 WGK 2
RTECS LY2625000
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 190 | 欧洲Eur. ≥ 66 | 東京Tokyo ≥ 82 | 香港与北京 ≥ 55