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硫酸卡那霉素,Kanamycin sulfate from Streptomyces kanamyceticus;Cell Culture-Tested, Calbiochem®

别名:卡那霉素硫酸酯来源于卡那霉素链霉菌;卡那霉素A;卡那霉素碱硫酸盐;卡那霉素硫酸盐;Kanamycin A;Kanamycin sulfate salt

CAS号 25389-94-0 经验分子式(希尔表示法) C18H36N4O11 · xH2SO4 分子量 484.50 (free base basis)
货号(SKU): 420411
CAS号: 25389-94-0
MDL号: MFCD00070253
增值税发票 √ 免费货运 [顺丰 联邦] √
¥941.09

产品描述

An aminoglycoside antibiotic effective against Gram-positive and Gram-negative organisms. Inhibitor of protein biosynthesis that acts on the 30S ribosome, causing misreading of the genetic code.

一种有效对抗革兰氏阳性和革兰氏阴性生物的氨基糖苷类抗生素。 作用于30S核糖体的蛋白质生物合成抑制剂,导致遗传密码的误读。

General description

Recommended working concentration: 100 µg/ml.

An aminoglycoside antibiotic effective against Gram-positive and Gram-negative organisms. Inhibitor of protein biosynthesis that acts on the 30S ribosome, causing misreading of the genetic code. May cause renal damage and ototoxicity.

An aminoglycoside antibiotic effective against Gram-positive and Gram-negative organisms. Inhibitor of protein biosynthesis that acts on the 70S ribosome, causing misreading of the genetic code. May cause renal damage and ototoxicity. Useful for the selection of kanamycin resistant plasmids in E. coli. Tested and found to be negative for cytotoxicity against HeLa cells. Contains more than 98% kanamycin A.

Contains >98% kanamycin A. Potency: ≥750 µg/mg

包装

5, 25 g in Glass bottle

Biochem/physiol Actions

Primary Target
protein biosynthesis that acts on the 30S ribosome

Warning

Toxicity: Carcinogenic / Teratogenic (D)

Reconstitution

Following reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.

Other Notes

Lech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
Cardon, G.H., et al. 1993. Plant J.3, 773.
Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties1, 690.
Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother.6, 516.
Umezawa, S., et al. 1968. J. Antibiot.21, 367.

性质

Quality Level100
formsolid
mfr. no.Calbiochem®
storage conditionOK to freeze
storage conditions+15C to +30C
colorwhite to off-white
solubilitywater: 10 mg/mL
shipped inambient
InChI1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1
InChI keyOOYGSFOGFJDDHP-KMCOLRRFSA-N


安全信息

符号
GHS08  GHS08
信号词 Danger
危害声明 H360D
警示性声明 P201 - P308 + P313
个人防护装备 EyeshieldsGlovestype N95 (US)
危害码 (欧洲) T
风险声明 (欧洲) 61
安全声明 (欧洲) 53-45
RIDADR NONH for all modes of transport
WGK德国 WGK 2
RTECS NZ3225030
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 190 | 欧洲Eur. ≥ 66 | 東京Tokyo ≥ 82 | 香港与北京 ≥ 55