盐酸阿霉素 [盐酸多柔比星]，Doxorubicin hydrochloride [DOX]；suitable for fluorescence, 98.0-102.0% (HPLC)

生物来源

synthetic

质量水平

200

测定

98.0-102.0% (HPLC)

形式

solid

颜色

orange to dark red

mp

216 °C (dec.) (lit.)

溶解性

H₂O: 50 mg/mL, clear, orange to red
DMSO: soluble
THF: soluble
ethanol: soluble
methanol: soluble

荧光

λ_ex 470 nm; λ_em 585 nm in ethanol

适用性

suitable for fluorescence

抗生素抗菌谱

neoplastics

作用机制

DNA synthesis | interferes
enzyme | inhibits

储存温度

2-8°C

SMILES string

Cl[H].COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO

InChI

1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1

InChI key

MWWSFMDVAYGXBV-RUELKSSGSA-N

Gene Information

human ... TOP2A(7153)

象形图

GHS07,GHS08

警示用语：

Danger

危险声明

H302 - H340 - H350 - H360FD

预防措施声明

P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313

危险分类

Acute Tox. 4 Oral - Carc. 1B - Muta. 1B - Repr. 1B

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges