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盐酸吉西他滨 [dFdC, dFdCyd]，Gemcitabine hydrochloride；≥98% (HPLC)

别名：吉西他滨盐酸盐；2';-脱氧-2',2'-二氟胞苷；盐酸吉西他宾；吉西他宾盐酸盐；2′-Deoxy-2′,2′-difluorocytidine；dFdC；Gemzar (Lilly)；LY-188011；dFdC；dFdCyd

CAS号 122111-03-9 经验分子式（希尔表示法） C9H11F2N3O4 · HCl 分子量 299.66 MDL number MFCD01735988 PubChem Substance ID 329799951 NACRES NA.77

品牌: 西格玛 Sigma-Aldrich

货号（SKU）: G6423

CAS号: 122111-03-9

MDL号: MFCD01735988

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目录价.SKU-Variant

10mg
50mg [+¥1,928.00]
1g [+¥7,710.00]
5g [+¥20,413.00]

¥732.00

数量:

产品描述

一种DNA合成抑制剂, 在BxPC-3, Mia Paca-2, PANC-1, PL-45和AsPC-1细胞中的IC50分别为37.6, 42.9, 92.7, 89.3 和131.4 nM

包装

10, 50 mg in glass bottle

Biochem/physiol Actions

吉西他滨是诊所和研究实验室中广泛使用的抗肿瘤药物。它是一种抗肿瘤药和抗代谢药。

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC^®¹²⁸⁰), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

法律信息

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

性质

Quality Level	100
assay	≥98% (HPLC)
form	powder
storage condition	desiccated
	protect from light
solubility	H₂O: ≥10 mg/mL
originator	Eli Lilly
storage temp.	room temp
SMILES string	Cl.NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)C2(F)F
InChI	1S/C9H11F2N3O4.ClH/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17;/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17);1H/t4-,6-,7-;/m1./s1
InChI key	OKKDEIYWILRZIA-OSZBKLCCSA-N
Gene Information	human ... POLA1(5422), POLA2(23649), POLD1(5424), POLD2(5425), POLD3(10714), POLD4(57804), POLE(5426), POLE2(5427), POLE3(54107), PRIM1(5557), PRIM2(5558), RRM1(6240), RRM2(6241), RRM2B(50484)

安全信息

符号

GHS08

信号词 Danger

危害声明 H360

警示性声明 P201 - P308 + P313

危害码 (欧洲) Xn

风险声明 (欧洲) 63-62

安全声明 (欧洲) 53-36/37

RIDADR NONH for all modes of transport

WGK德国 WGK 3

商品规格

属性名称	属性值
储存温度 Storage temp.	常温阴凉避光
全球实时库存 Availability √	美国St. Louis ≥ 88 \| 欧洲Eur. ≥ 126 \| 東京Tokyo ≥ 46 \| 香港与北京 ≥ 62

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盐酸吉西他滨 [dFdC, dFdCyd]，Gemcitabine hydrochloride；≥98% (HPLC)

产品描述

包装

Biochem/physiol Actions

Features and Benefits

法律信息

性质

安全信息

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