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白藜芦醇,Resveratrol;BSZH grade, ≥99% (HPLC)

别名:芪三酚;3,4′,5-三羟基-反式-二苯乙烯;5-[(1E)-2-(4-羟基苯基)乙烯基]-1,3-苯二酚;3,4',5-三羟基芪;3,4′,5-Trihydroxy-trans-stilbene,5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol

CAS号 501-36-0 经验分子式(希尔表示法) C14H12O3 分子量 228.24 MDL number MFCD00133799 PubChem Substance ID 24278055 NACRES NA.25
制造商品牌: BSZH 科学公司
货号(SKU): RV4709
CAS号: 501-36-0
MDL号: MFCD00133799
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HK$642.54

产品描述

白藜芦醇是一种天然多酚,具有抗氧化,抗炎,保护心脏和抗癌的特性, 它的靶点广泛,如:mTOR,JAK,β-amyloid,Adenylyl cyclase,IKKβ,DNA polymerase等。

Application

Resveratrol has been used:
• in entrapment experiment
• to study its neuroprotective effect on retinal neuronal cell death mediated by diabetes-induced activation of Ca2+/calmodulin-dependent protein kinase II
• as a standard in the assessment of stilbene content in grapevine leaf by in vivo fluorometry

COX-1 选择性抑制剂。

Biochem/physiol Actions

Resveratrol is a phenolic phytoalexin found in grape skin and other plants. It has intracellular antioxidant activity and activates sirtuin 1 (SIRT1), a nicotinamide adenine dinucleotide (NAD+)-dependent histone deacetylase involved in mitochondrial biogenesis and the enhancement of peroxisome proliferator-g-activated receptor coactivator-1a (PGC-1a) and FOXO (forkhead box) activity. The anti-diabetic, neuroprotective and anti-adipogenic actions of resveratrol may be mediated via SIRT1 activation. Resveratrol has antiviral action against Herpes simplex virus-1 (HSV1) and HSV2. It also exhibits antitumor and phytoestrogenic biological activities. Resveratrol is known to prolong life in many species by mediating several physiological events.

Preparation Note

可溶于乙醇、DMSO和丙酮。 仅有极少量的可溶于水(3 mg/100 mL)。

性质

biological sourceplant root (bushy knotweed)
assay≥99% (HPLC)
formpowder
solubilityacetone: 50 mg/mL, clear, faintly yellow
storage temp.−20°C
SMILES stringOc1ccc(cc1)\C=C\c2cc(O)cc(O)c2
InChI1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+
InChI keyLUKBXSAWLPMMSZ-OWOJBTEDSA-N
Gene Informationhuman ... AR(367), CYP1A2(1544), ESR1(2099), SIRT1(23411)
mouse ... Nos2(18126)
rat ... Esr1(24890)


安全信息

危害码 (欧洲) Xi
风险声明 (欧洲) 36
安全声明 (欧洲) 26
RIDADR NONH for all modes of transport
WGK德国 WGK 3
RTECS CZ8987000
商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 190 | 欧洲Eur. ≥ 66 | 東京Tokyo ≥ 82 | 香港与北京 ≥ 55
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