甲硝唑，Metronidazole；Pharmaceutical Secondary Standard; Certified Reference Material

图片 甲硝唑，Metronidazole；Pharmaceutical Secondary Standard; Certified Reference Material
别名：甲硝唑标准品；2-甲基-5-硝基-1-咪唑乙醇；2-甲基-5-硝基咪唑-1-乙醇；甲硝哒唑；呋钠捷；甲硝基羟乙唑；咪唑尼达；灭滴唑；硝基羟乙唑；夫纳捷；弗来格；1-(2-羟乙基)-2-甲基-5-硝基咪唑；2-甲基-5-硝基-1H-咪唑-1-乙醇；2-(2-甲基-4-硝基-1-咪唑基)乙醇；2-Methyl-5-nitroimidazole-1-ethanol；Eumin; Bexon; Klont; 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-;Metronidazole; Atrivyl; Clont; FLACYL; Klion; Meronidal; Thivazol

Empirical Formula (Hill Notation): C6H9N3O3 CAS号: 443-48-1 分子量: 171.15 Beilstein: 611683 EC 号: 207-136-1 MDL编号: MFCD00009750 PubChem化学物质编号: 329823082
制造商品牌: 色谱科 Supelco , 西格玛 Sigma-Aldrich
货号（SKU）: PHR1052
CAS号: 443-48-1
MDL号: MFCD00009750
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √

说明

甲硝唑是一种5-硝基咪唑衍生物，是对抗厌氧原生动物和细菌引起的疾病的有效药物。已知对缺氧的肿瘤细胞产生放射增敏作用。
甲硝唑可用作通过色谱技术测定药物制剂中分析物的药物参考标准。

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Metronidazole is a 5-nitroimidazole derivative that is an effective agent against the diseases caused by anaerobic protozoa and bacteria. It is known to exert radio-sensitizing impact on hypoxic tumour cells.
 

应用

Metronidazole may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
 

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
 

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
 

附注

To see an example of a Certificate of Analysis for this material enter LRAC0264 in the slot below. This is an example certificate only and may not be the lot that you receive.
 
 

属性

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP 603
traceable to Ph. Eur. M1850000
traceable to USP 1442009

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

159-161 °C (lit.)

application(s)

pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

SMILES string

CC1=NC=C([N+]([O-])=O)N1CCO

InChI

1S/C6H9N3O3/c1-5-7-4-6(9(11)12)8(5)2-3-10/h4,10H,2-3H2,1H3

InChI key

VAOCPAMSLUNLGC-UHFFFAOYSA-N

 

安全信息

象形图

Health hazard
GHS08

警示用语：

Danger

危险声明

H340 - H350 - H373

危险分类

Carc. 1B - Muta. 1B - STOT RE 2

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 50 | 欧洲Eur. ≥ 12 | 東京Tokyo ≥ 20 | 香港与北京 ≥ 50
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