甲氨蝶呤 [氨甲喋呤]，Methotrexate [MTX]； suitable for manufacturing use, 98.0-102.0%

图片 甲氨蝶呤 [氨甲喋呤]，Methotrexate [MTX]； suitable for manufacturing use, 98.0-102.0%
别名：(+)-氨甲蝶呤；MTX；氟安定；氨甲叶酸；4-氨基-N10-甲基巯基-L-谷氨酸；(+)-Amethopterin, 4-Amino-10-methylfolic acid, 4-Amino-N10-methylpteroyl-L-glutamic acid, Antifolan, MTX, Methotrexate, Methylaminopterin

Empirical Formula (Hill Notation): C20H22N8O5 CAS号: 59-05-2 分子量: 454.44 Beilstein: 70669 EC 号: 200-413-8 MDL编号: MFCD00064370 PubChem化学物质编号: 329817917 NACRES: NA.21
制造商品牌: SAFC , 西格玛 Sigma-Aldrich
货号（SKU）: M7824
CAS号: 59-05-2
MDL号: MFCD00064370
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √

说明

一般描述

抑制胸苷酸合成酶，是一种非选择性的嘌呤从头合成抑制剂，具有显著的毒性特征，包括肝毒性、肺炎和骨髓抑制。强效叶酸拮抗剂。在HL-60人白血病细胞中诱导凋亡。还可用作抗肿瘤剂。
Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
 

法律信息

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
 
 

属性

生物来源

synthetic

质量水平

400

形式

powder

适用性

suitable for manufacturing use

储存温度

−20°C

SMILES string

CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1

InChI key

FBOZXECLQNJBKD-ZDUSSCGKSA-N

Gene Information

human ... DHFR(1719)

 

安全信息

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Oral - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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