生长抑素，Somatostatin [SRIF]；powder, BioReagent, suitable for cell culture, ≥97% (HPLC)

图片 生长抑素，Somatostatin [SRIF]；powder, BioReagent, suitable for cell culture, ≥97% (HPLC)
别名：促生长素释放抑制因子；生长抑素-14；生长激素释放抑制因子；Growth hormone release inhibiting factor；SRIF；Somatostatin-14；Somatotropin release inhibiting factor

Empirical Formula (Hill Notation): C76H104N18O19S2 CAS号: 38916-34-6 分子量: 1637.88 Beilstein: 6436064 EC 号: 254-186-5 MDL编号: MFCD00076762 PubChem化学物质编号: 24899493 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: S1763
CAS号: 38916-34-6
MDL号: MFCD00076762
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说明

Amino Acid Sequence

Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys
 

应用

Somatostatin has been used in cell culture.[1] It has also been used in the study of glucose-6-phosphate dehydrogenase activity in monolayer cultures of thyroid epithelial cells.[2]
 

生化/生理作用

Somatostatin regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones.
Somatostatin (SST) is a peptide. It performs several functions like anti-proliferation, pro-apoptosis and anti-migration.[3] Somatostatin performs physiological activities with the help of various G protein-coupled receptor subtypes (SST receptor (SSTR)-1, SSTR2A, SSTR2B, and SSTR3–5).[4]
 

外形

powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw
 

重悬

To prepare 2 μg/ml stock solution, dissolve in 5 ml sterile culture medium per μg somatostatin.
 
 

属性

生物来源

synthetic (organic)

质量水平

200

产品线

BioReagent

测定

≥97% (HPLC)

形式

powder

technique(s)

cell culture | mammalian: suitable

溶解性

H2O: 1 mg/mL

运输

ambient

储存温度

−20°C

SMILES string

[H]N1[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc4c[nH]c5ccccc45)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc6ccccc6)C(=O)N[C@@H]([C@@H](C)O)C(=O)NC(CO)C(=O)N[C@@H](CSSC[C@H](NC(=O)CNC(=O)[C@H](C)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C1=O)C(O)=O

InChI

1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57?,58-,59-,62-,63-/m0/s1

InChI key

NHXLMOGPVYXJNR-FQSIDJEASA-N

Gene Information

human ... SSTR1(6751) , SSTR2(6752) , SSTR3(6753) , SSTR4(6754) , SSTR5(6755)

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type N95 (US)

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 50 | 欧洲Eur. ≥ 12 | 東京Tokyo ≥ 20 | 香港与北京 ≥ 50
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