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球姜酮 [花姜酮],Zerumbone;≥98% (HPLC)

别名:(2E,6E,10E)-2,6,9,9-四甲基环十一烷-2,6,10-三烯-1-酮;球姜酮(6CI,7CI);(2E,6E,10E)-2,6,9,9-tetramethylcycloundeca-2,6,10-trien-1-one, Zerumbone (6CI,7CI)

CAS号 471-05-6 经验分子式(希尔表示法) C15H22O 分子量 218.33 MDL number MFCD03700769 PubChem Substance ID 329831611 NACRES NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): Z3902
CAS号: 471-05-6
MDL号: MFCD03700769
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¥882.17

产品描述

General description

Zerumbone is a monocyclic sesquiterpene compound, which is extracted from the essential oil of Zingiber zerumbet rhizomes.[1] It has antimicrobial, antinociceptive, antiatherosclerotic, hepatoprotective and antioxidant properties. Zerumbone also has anti-inflammatory and anticancer effects.[2]

Application

Zerumbone has been used:
• for liquid chromatography with mass spectrometry (LC-MS-MS)[3][4]
• to investigate its potential application in the prevention
• treatment of esophageal squamous cell carcinomas (ESCC)[5]

包装

10, 50 mg in glass bottle

Biochem/physiol Actions

Zerumbone 是一种 TRAIL 诱导的细胞凋亡增强剂。它通过上调 DR4 和 DR5 的表达及下调 cFLIP 而加强 TRAIL 诱导的细胞凋亡。Zerumbone 对正常人内皮细胞和皮肤成纤维细胞几乎无细胞毒性作用。Zerumbone 是从姜属植物 Zingiber zerumbet Smith(野生姜)中分离得到的一种倍半萜烯。

性质

Quality Level  100
assay  ≥98% (HPLC)
form  powder
color  white to off-white
solubility  DMSO: ≥10 mg/mL
storage temp.  2-8°C
SMILES string  C\C1=C/CC(C)(C)\C=C\C(=O)\C(C)=C\CC1
InChI  1S/C15H22O/c1-12-6-5-7-13(2)14(16)9-11-15(3,4)10-8-12/h7-9,11H,5-6,10H2,1-4H3/b11-9+,12-8+,13-7+
InChI key  GIHNTRQPEMKFKO-SKTNYSRSSA-N


安全信息

符号 
信号词 Warning
危害声明 H317 - H400
警示性声明 P273 - P280 - P302 + P352
危害码 (欧洲) Xi,N
风险声明 (欧洲) 43-50
安全声明 (欧洲) 36/37-60-61
RIDADR UN 3077 9 / PGIII
WGK德国 WGK 3
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 60 | 欧洲Eur. ≥ 21 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 10
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