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烟酸,Nicotinic acid [维生素B3];≥99.5% (HPLC)

别名:3-吡啶甲酸, 吡啶-3-羧酸,尼亚生,尼克酸,抗癞皮病因子,抗糙皮病因子,维生素 B3,尼古丁酸,维生素PP ,3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid, Vitamin B3

CAS号 59-67-6 经验分子式(希尔表示法) C6H5NO2 分子量 123.11 Beilstein/REAXYS Number 109591 EINECS 编号 200-441-0 MDL number MFCD00006391 PubChem Substance ID 57652411 NACRES NA.26
货号(SKU): 72309
CAS号: 59-67-6
MDL号: MFCD00006391
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£51.32

产品描述

General description

Nicotinic acid, also referred as Niacin or vitamin B3, is a water soluble vitamin.[3] It is present in vitamin-enriched bread, liver, meat, fish, poultry, potatoes, green vegetables, peanuts and cereals.[4]

Application

Nicotinic acid has been used as a standard in NAD+ precursor rescue experiments.[7] It has also been used as a vitamin supplement in various culture media such as complete medium (CM)[8] and synthetic medium.[9]

Biochem/physiol Actions

Nicotinic acid or Niacin regulates lipid metabolism by reducing low density lipoprotein (LDL), increasing high-density lipoprotein (HDL) and by inhibiting the progression of atherosclerosis and coronary artery lesions.[4][5] Niacin deficiency leads to pellagra.[4] In addition to vitamin supplement, niacin is also used as a broad spectrum lipid drug.[6]

Other Notes

Coenzyme and Cofactors, vol 2: Pyridine Nucleotide Coenzymes[1][2]

性质

Quality Level200
biological sourcesynthetic
assay≥99.5% (HPLC)
formpowder
impurities≤0.2% water
ign. residue≤0.05%
colorcolorless to white
mp234-238 °C
236-239 °C (lit.)
SMILES stringOC(=O)c1cccnc1
InChI1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)
InChI keyPVNIIMVLHYAWGP-UHFFFAOYSA-N
Gene Informationhuman ... CYP1A2(1544)
rat ... Chrnb2(54239)


安全信息

符号
GHS07  GHS07
信号词
Warning
危害声明 H319
警示性声明 P305 + P351 + P338
个人防护装备 dust mask type N95 (US)EyeshieldsGloves
危害码 (欧洲) Xi
风险声明 (欧洲) 36
安全声明 (欧洲) 26
RIDADR NONH for all modes of transport
WGK德国 WGK 1
RTECS QT0525000
闪点(华氏) 379.4 °F - closed cup
闪点(摄氏) 193 °C - closed cup
商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 190 | 欧洲Eur. ≥ 66 | 東京Tokyo ≥ 82 | 香港与北京 ≥ 55
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