别名:泰乐菌素酒石酸盐;酒石酸泰乐菌素;泰农;泰乐二甲基酸;酒石酸太东菌素;2-((4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-(((2R,3R,4R,5S,6R)-5-(((2S,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-16-ethyl-4-hydroxy-15-((((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy);2-((4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-(((2R,3R,4R,5S,6R)-5-(((2S,4R,5S,6S)-4,5-二羟基-4,6-二甲基四氢-2H-吡喃-2-基)氧基)-4-(二甲基氨基)-3-羟基-6-甲基四氢-2H-吡喃-2-基)氧基)-16-乙基-4-羟基-15-((((2R,3R,4R,5R,6R)-5-羟基-3,4-二甲氧基-6-甲基四氢-2H-吡喃-2-基)氧基)甲基)-5,9,13-三甲基-2,10-二氧杂氧杂环十六烷-11,13-二烯-7-基)乙醛 (2R,3R)-2,3-二羟基琥珀酸酯
MDL number MFCD07783824 PubChem Substance ID 24900364 NACRES NA.76
货号(SKU): T6271
CAS号: 74610-55-2
MDL号: MFCD07783824
产品描述
General description
Chemical structure: macrolide
包装
1, 5, 10 g in poly bottle
Application
Tylosin is a mcrolide antibiotic commonly used in veterinary medicine. It has been used to study protein synthesis at the 50S ribosome, implant site abscess prevention in cattle, disposition kinetics and Mycoplasma gallisepticumand Mycoplasma meleagridis infections. It is recommended for use in cell culture applications at 8 mg/L.
Biochem/physiol Actions
Mode of Action: Tylosin Tartrate inhibits bacterial protein synthesis by binding to the 50S (L27 protein) ribosome.
Antimicrobial Spectrum: This product acts against gram-positive bacteria and mycoplasma.
Components
泰乐菌素 A、B、C 和 D 酒石酸盐的混合物。
Caution
Stock solutions should be filter sterilized and stored at 2-8°C. These solutions are stable at 37°C for 3 days.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
性质
product line | BioReagent |
form | powder |
potency | ≥800 units/mg tylosin |
application(s) | cell culture | mammalian: suitable |
color | off-white to yellow |
solubility | H2O: ≤50 mg/mL |
Mode of action | protein synthesis | interferes |
antibiotic activity spectrum | Gram-positive bacteria |
| mycoplasma |
storage temp. | 2-8°C |
SMILES string | O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(C)=C\[C@@H]1CO[C@@H]4O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]4OCInChI | 1S/C46H77NO17.C4H6O6/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35;5-1(3(7)8)2(6)4(9)10/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3;1-2,5-6H,(H,7,8)(H,9,10)/b15-14+,23-18+;/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-;1-,2-/m11/s1InChI key | ICVKYYINQHWDLM-KBEWXLTPSA-N | | |
安全信息
RIDADR NONH for all modes of transport