泰乐菌素酒石酸酯 [酒石酸泰洛星]，Tylosin tartrate；powder, BioReagent, suitable for cell culture, ≥800 units/mg tylosin

别名：酒石酸泰乐菌素；泰乐菌素酒石酸盐；泰农；泰乐二甲基酸；酒石酸太东菌素；2-((4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-(((2R,3R,4R,5S,6R)-5-(((2S,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-16-ethyl-4-hydroxy-15-((((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)；2-((4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-(((2R,3R,4R,5S,6R)-5-(((2S,4R,5S,6S)-4,5-二羟基-4,6-二甲基四氢-2H-吡喃-2-基)氧基)-4-(二甲基氨基)-3-羟基-6-甲基四氢-2H-吡喃-2-基)氧基)-16-乙基-4-羟基-15-((((2R,3R,4R,5R,6R)-5-羟基-3,4-二甲氧基-6-甲基四氢-2H-吡喃-2-基)氧基)甲基)-5,9,13-三甲基-2,10-二氧杂氧杂环十六烷-11,13-二烯-7-基)乙醛 (2R,3R)-2,3-二羟基琥珀酸酯

MDL编号: MFCD07783824 PubChem化学物质编号: 24900364 NACRES: NA.76

制造商品牌: 西格玛 Sigma-Aldrich

货号（SKU）: T6271

CAS号: 74610-55-2

MDL号: MFCD07783824

签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √

说明

泰乐菌素是兽医学中常用的mcrolide抗生素。它已被用于研究50S核糖体的蛋白质合成，牛的植入部位脓肿预防，处置动力学和鸡毒支原体和支原体感染。建议以8 mg/L的浓度用于细胞培养应用。

一般描述

Chemical structure: macrolide

应用

Tylosin is a mcrolide antibiotic commonly used in veterinary medicine. It has been used to study protein synthesis at the 50S ribosome, implant site abscess prevention in cattle, disposition kinetics and Mycoplasma gallisepticumand Mycoplasma meleagridis infections. It is recommended for use in cell culture applications at 8 mg/L.

生化/生理作用

Mode of Action: Tylosin Tartrate inhibits bacterial protein synthesis by binding to the 50S (L27 protein) ribosome.
Antimicrobial Spectrum: This product acts against gram-positive bacteria and mycoplasma.

组分

泰乐菌素 A、B、C 和 D 酒石酸盐的混合物。

注意

Stock solutions should be filter sterilized and stored at 2-8°C. These solutions are stable at 37°C for 3 days.

其他说明

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

属性

产品线

BioReagent

质量水平

200

形式

powder

效能

≥800 units/mg tylosin

储存条件

(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)

technique(s)

cell culture | mammalian: suitable

颜色

off-white to yellow

溶解性

H₂O: ≤50 mg/mL

抗生素抗菌谱

Gram-positive bacteria
mycoplasma

作用机制

protein synthesis | interferes

储存温度

2-8°C

SMILES string

O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(C)=C\[C@@H]1CO[C@@H]4O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]4OC

InChI

1S/C46H77NO17.C4H6O6/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35;5-1(3(7)8)2(6)4(9)10/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3;1-2,5-6H,(H,7,8)(H,9,10)/b15-14+,23-18+;/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-;1-,2-/m11/s1

InChI key

ICVKYYINQHWDLM-KBEWXLTPSA-N

安全信息

象形图

GHS08

警示用语：

Danger

危险声明

H317 - H334

预防措施声明

P280 - P302 + P352

危险分类

Resp. Sens. 1 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

商品规格

属性名称	属性值
储存温度 Storage temp.	2-8°C冷藏
全球实时库存 Availability √	美国St. Louis ≥ 20 \| 欧洲Eur. ≥ 16 \| 東京Tokyo ≥ 5 \| 香港与北京 ≥ 20

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