柯里拉京，Corilagin；≥98% (HPLC)

图片 柯里拉京，Corilagin；≥98% (HPLC)
Empirical Formula (Hill Notation): C27H22O18 CAS号: 23094-69-1 分子量: 634.45 MDL编号: MFCD00238565 PubChem化学物质编号: 329799812 NACRES: NA.25
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: G0424
CAS号: 23094-69-1
MDL号: MFCD00238565
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说明

Corilagin 是一种多酚单宁酸，是存在于各种植物物种中的主要生物活性化合物。它是 Phyllanthus urinaria 和Terminalia catappa L 提取物的活性成分，用于治疗各种疾病。Corilagin 已被用于研究其通过诱导细胞凋亡和受活性氧释放调节的自噬来抑制乳腺癌生长的作用。

Corilagin 具有多种生物活性，如抗炎、抗病毒、抗氧化、保肝、抗菌、抗凝血、降血脂和降血压。已经注意到它还具有抗肿瘤、抗增殖、凋亡和自噬能力。已发现 Corilagin 可降低 β-内酰胺对耐甲氧西林金黄色葡萄球菌 (MRSA) 的最低抑菌浓度 (MIC)。Corilagin 是一种多酚，特别是一种可水解的单宁，存在于中药草药制剂中。据报道，它具有抗炎和抗肿瘤活性。

一般描述

Corilagin is a polyphenolic tannic acid and a major bioactive compound present in various plant species. It is an active component of Phyllanthus urinaria and Terminalia catappa L extract used to treat various ailments.
 

应用

Corilagin has been used to study its inhibitory effect on the growth of breast cancer by inducing apoptosis and autophagy regulated by the release of reactive oxygen species.
 

生化/生理作用

Corilagin shows a variety of biological activities such as anti-inflammatory, anti-viral, anti-oxidant, hepatoprotective, antibacterial, anti-coagulant, hypolipemic and hypotensive. It has been noted to possess anti-tumor, antiproliferative, apoptotic, and autophagic abilities as well. Corilagin has been found to reduce the minimum inhibitory concentration (MIC) of β-lactams against Methicillin-resistant Staphylococcus aureus (MRSA).
Corilagin is a polyphenol, specifically a hydrolyzable tannin, found in Traditional Chinese Medicine herbal preparations. It is reported to have anti-inflammatory and anti-tumor activities.
 
 

属性

质量水平

200

测定

≥98% (HPLC)

形式

powder

溶解性

H2O: 1 mg/mL, clear, colorless

储存温度

2-8°C

SMILES string

O[C@@H]1[C@H]2COC(=O)c3cc(O)c(O)c(O)c3-c4c(O)c(O)c(O)cc4C(=O)O[C@@H]1[C@@H](O)[C@@H](O2)OC(=O)c5cc(O)c(O)c(O)c5

InChI

1S/C27H22O18/c28-9-1-6(2-10(29)16(9)32)24(39)45-27-22(38)23-19(35)13(43-27)5-42-25(40)7-3-11(30)17(33)20(36)14(7)15-8(26(41)44-23)4-12(31)18(34)21(15)37/h1-4,13,19,22-23,27-38H,5H2/t13-,19-,22-,23+,27+/m1/s1

InChI key

TUSDEZXZIZRFGC-XIGLUPEJSA-N

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 10 | 欧洲Eur. ≥ 8 | 東京Tokyo ≥ 6 | 香港与北京 ≥ 60
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