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木兰脂素,Magnolin;≥95% (HPLC)

别名:(+)-木兰素;(1S,3aR,4S,6aR)-1-(3,4-二甲氧基苯基)四氢-4-(3,4,5-三甲氧基苯基)-1H,3H-呋喃[3,4-c]呋喃;(1S,3aR,4S,6aR)-1-(3,4-二甲氧基苯基)四氢-4-(3,4,5-三甲氧基苯基)-1H,3H-呋喃[3,4-c]呋喃;木兰素;间树脂醇二甲醚;(+)-Magnolin, (1S,3aR,4S,6aR)-1-(3,4-Dimethoxyphenyl)tetrahydro-4-(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan, (1S,3aR,4S,6aR)-1-(3,4-Dimethoxyphenyl)tetrahydro-4-(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan, Magnolin, Medioresinol dimethyl ether

Empirical Formula (Hill Notation): C23H28O7 CAS号: 31008-18-1 分子量: 416.46 MDL编号: MFCD07783722
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): SML2438
CAS号: 31008-18-1
MDL号: MFCD07783722
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¥587.19

说明

木兰脂素是 Magnolia flos 的主要成分,具有抗炎、抗氧化和扩张血管的活性。 木兰脂素通过靶向 ERKs/RSK2 信号传导来抑制细胞迁移和侵袭。木兰脂素还可以防止大鼠对比剂肾病 (CIN) 中的肾小管坏死、细胞凋亡和肾功能恶化。

生化/生理作用

Magnolin is a main component of Magnolia flos the exhibits anti-inflammatory, antioxidative, and vasodilatory activities. Magnolin inhibits cell migration and invasion by targeting the ERKs/RSK2 signaling. Also magnolin protects against renal tubular necrosis, apoptosis, and the deterioration of renal function in contrast-induced nephropathy (CIN) in rats.
 
 

属性

测定

≥95% (HPLC)

形式

powder

旋光性

[α]/D +46 to +56°, c = 0.5 in chloroform-d

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear

储存温度

−20°C

SMILES string

[H][C@]12[C@]([C@@H](C3=CC(OC)=C(OC)C(OC)=C3)OC2)([H])CO[C@@H]1C4=CC=C(OC)C(OC)=C4

InChI

1S/C23H28O7/c1-24-17-7-6-13(8-18(17)25-2)21-15-11-30-22(16(15)12-29-21)14-9-19(26-3)23(28-5)20(10-14)27-4/h6-10,15-16,21-22H,11-12H2,1-5H3/t15-,16-,21+,22+/m0/s1

InChI key

MFIHSKBTNZNJIK-RZTYQLBFSA-N

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 60 | 欧洲Eur. ≥ 21 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 10
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