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曲拉通X100 (还原型),Triton™ X-100 reduced

别名:聚氧代乙烯(10)异辛基环己基醚;Polyoxyethylene (10) isooctylcyclohexyl ether

线性分子式: 4-(C8H17)C6H10(OCH2CH2)nOH, n~10 CAS号: 92046-34-9 MDL编号: MFCD00132505 NACRES: NA.23
制造商品牌: Sigma-Aldrich
货号(SKU): 282103
CAS号: 92046-34-9
MDL号: MFCD00132505
技术支持 √ 增值税发票 √ 免费送货 √ 质量保障 √
¥1,238.97

说明

一般描述

当 TX-100 的苯部分被完全氢化为环己烷衍生物时,形成还原的 Triton X-100(RTX-100)。RTX-100 可能促进酶的消化,并且对细菌视紫红质的光异构化也有一定的影响。[1]
Triton X-100 reduced is a versatile nonionic surfactant with a hydrophilic polyethylene oxide chain, widely utilized as a laboratory detergent. Its applications span various areas, including cell biology and biochemical research. This detergent is commonly employed for tasks such as cell lysis to extract proteins or organelles, permeabilizing the membranes of living cells, and serving as a crucial component in lysis buffers. Triton X-100 plays a key role in the isolation of lipid rafts, contributing to enhanced solubility and dispersibility of substances. With a reduced polyoxyethylene content of approximately 10, Triton X-100 exhibits excellent wetting properties and facilitates emulsification.

In biochemical and cell biology research, Triton X-100 is instrumental in solubilizing membrane-bound proteins and isolating lipid rafts. Its unique properties allow for the preservation of the native conformation of proteins obtained from cellular membranes in solution. Triton X-100 reduced is derived from the full hydrogenation of the benzene moiety of TX-100 to a cyclohexane derivative. This modified version, RTX-100, has demonstrated potential in enhancing enzyme digestion and influencing the photoisomerization of bacteriorhodopsin, showcasing its versatility and utility in advanced research applications.
 

应用

还原型 Triton X-100 已用于:
  • 作为 LB-TT 的一种成分,用于从大鼠脑中提取总蛋白[2]
  • 在 ADP-Glo 测定和细胞磷酸腺苷三磷酸酶(ATP 酶)测定中[3]
  • 在磷酸盐缓冲盐水(PBS)溶液中,用于成纤维细胞在 5′-乙炔-尿苷染色、免疫荧光和免疫标记中的透化[4]

特点和优势

  • Non-ionic surfactant
  • Reduced polyoxyethylene content (~10)
  • Improves solubility and dispersibility of substances
  • Excellent wetting properties
  • Enhances emulsification
  • High purity product for research applications

法律信息

Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow
 
 

属性

折射率

n20/D 1.473 (lit.)

密度

1.029 g/mL at 25 °C (lit.)

InChI

1S/C28H56O8/c1-27(2,3)24-28(4,5)25-6-8-26(9-7-25)36-23-22-35-21-20-34-19-18-33-17-16-32-15-14-31-13-12-30-11-10-29/h25-26,29H,6-24H2,1-5H3

InChI key

QQJNBKDKLMCALZ-UHFFFAOYSA-N

 

安全信息

象形图

Exclamation markEnvironment

警示用语:

Warning

危险分类

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(F)

235.4 °F - closed cup

闪点(C)

113 °C - closed cup

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16
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