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抑肽酶来源于牛肺,Aprotinin from bovine lung [BPTI];lyophilized powder, 3-8 TIU/mg solid, BioReagent, suitable for cell culture

别名:胰蛋白酶抑制剂(碱性),胰腺胰蛋白酶抑制剂,胰蛋白酶-激肽释放酶抑制剂,胰蛋白酶抑制剂,胰腺型(bpti),pancreatic trypsin inhibitor, trypsin inhibitor, pancreas type (bpti), trypsin-kallikrein inhibitor,Trasylol, Trypsin inhibitor (basic)

CAS号 9087-70-1 经验分子式(希尔表示法) C284H432N84O79S7 分子量 6511.44 EINECS 编号 232-994-9 MDL number MFCD00130541 eCl@ss 32190102 NACRES NA.32
货号(SKU): A3428
CAS号: 9087-70-1
MDL号: MFCD00130541
增值税发票 √ 免费货运 [顺丰 联邦] √
¥1,871.49

产品描述

Application

Aprotinin from bovine lung has been used in insulin and glucagon-like peptide-1 assay.[2] It has also been used a in western blotting.[3][4]

抑肽酶被大量用作胰蛋白酶抑制剂。

包装

10, 25 mg in poly bottle

100, 250 mg in glass bottle

Biochem/physiol Actions

Aprotinin is a natural polypeptide of 58 amino acids. It possesses hemostatic/antiplasmin action and helps to reduce bleeding during surgeries. This prevents the necessity of blood transfusion.[1]

抑肽酶是一种竞争性丝氨酸蛋白酶抑制剂,可与酶的活性<WBR>位点组成稳定的复合酶并同时对其进行封闭。 这种结合是可逆的,而且绝大多数抑肽酶-蛋白酶复合物<WBR>可在极端的pH >10 or < 3水平时发生解离。 从结构上来说,抑肽酶是一种来自牛肺的单体球状蛋白,由58个氨基酸组成并排列在具有三个交联二硫键的单个多肽链中。

Unit Definition

When benzoyl-L-arginine ethyl ester (BAEE) is used as substrate one BAPNA unit is approx. 45BAEE μmolar units at pH8.0 at 25°C or approx. 9,000 BAEE A253 units at pH7.6 at 25°C.

一个胰蛋白酶抑制剂单位(TIU)可将两个胰蛋白酶单位的活性降低50%,而其中一个胰蛋白酶单位在pH 7.8和25℃下可每分钟水解1.0 μ摩尔的N-α-苯甲酰基-DL-精氨酸对硝基苯胺。另一种常用的单位是KIU,而1 TIU = 1,300 KIU。

Preparation Note

This product is a lyophilized powder that has been cell culture tested. It has an activity of 3-7 TIU/mg.

性质

Quality Level200
biological sourcebovine lung
product lineBioReagent
formlyophilized powder
specific activity3-8 TIU/mg solid
mol wt~6,500
application(s)cell culture | mammalian: suitable
solubilityH2O: 5 mg/mL
storage temp.2-8°C
InChI keyZPNFWUPYTFPOJU-UHFFFAOYSA-N
Gene Informationcow ... PTI(404172)


安全信息

个人防护装备 EyeshieldsGlovestype N95 (US)
RIDADR NONH for all modes of transport
WGK德国 WGK 1
RTECS YN5080000
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 88 | 欧洲Eur. ≥ 126 | 東京Tokyo ≥ 46 | 香港与北京 ≥ 62
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