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强阳离子交换树脂,Capto™ SP ImpRes ion exchange chromatography resin

Capto™ SP ImpRes 强阳离子交换填料具有高结合容量和小珠子尺寸,是工业纯化中可靠且稳健的精制步骤的理想选择。17546805;17546803;17546802;17546810;17546804
货号(SKU): 17546803
增值税发票 √ 免费送货 √ 订货电话:010-68689484
€165.69

With a high binding capacity and small bead size, Capto™ SP ImpRes strong cation exchanger is a good choice for reliable and robust polishing steps in industrial purification.

基于成熟的 Capto™ 平台和传统配体的高分辨率中间纯化和抛光树脂。与 Capto™ S 相比,粒径更小。
由于流速和床层高度的操作窗口大,因此工艺设计灵活。
高通量纯化易于优化和放大。
更高的制造生产率可提高流程经济性。
树脂满足工业对供应安全、稳健性能和监管支持的需求
专为大进料量而设计
Capto™ SP ImpRes 是一种强阳离子交换剂,适用于各种生物分子的高通量中间纯化和精制步骤。这种层析树脂是基于高流速琼脂糖 Capto™ 产品线的扩展高分辨率平台的一部分。

Capto™ SP ImpRes 将 Capto™ 树脂的高流动特性与小粒径相结合,提供出色的压力流动特性和令人印象深刻的分辨率。在更高流速和更高床层高度下运行的能力也增加了工艺设计的灵活性。

适合大规模净化工艺
Capto™ SP ImpRes 是一种 BioProcess™ 层析树脂,专为生物制药蛋白质的大规模纯化而开发。基于成熟的 Capto™ 基础基质和传统的离子基配体,它为提高生产力和直接的工艺开发提供了许多机会。

 

  • High-resolution intermediate purification and polishing resin based on the well-established Capto™ platform with traditional ligands. Smaller particle size compared with Capto™ S.
  • Flexible process design due to large operational window of flow rates and bed heights.
  • High throughput purifications easy to optimize and scale-up.
  • Higher manufacturing productivity enables improved process economy.
  • Resin fulfills industrial demands for security of supply, robust performance, and regulatory support

Designed for large feed volumes

Capto™ SP ImpRes is a strong cation exchanger for the high-throughput intermediate purification and polishing steps of a wide range of biomolecules. This chromatography resin is part of an expanded high-resolution platform based on the high-flow agarose Capto™ product line.

By combining the high-flow characteristics of Capto™ resin with a small particle size, Capto™ SP ImpRes delivers excellent pressure-flow properties with impressive resolution. The ability to run at higher flow rates and higher bed heights also increases flexibility in process design.

Suits large-scale purification processes

Capto™ SP ImpRes is a BioProcess™ chromatography resin developed for large-scale purification of biopharmaceutical proteins. Based on the well-established Capto™ base matrix and with traditional ionic group ligands, it provides many opportunities for improved productivity and straightforward process development.

 

ParameterCapto™ SP ImpRes, 1 L
Chromatography techniqueIon Exchange Chromatography 
BioProcess resinYes 
LigandSulfonate group 
Ion Exchanger TypeStrong cation exchanger 
MatrixHigh-flow agarose 
Particle Size36-44 μm (d50V
Binding Capacity/ml Chromatography Medium> 70 mg lysozyme, > 95 mg BSA 
Ionic Capacity0.13-0.16 mmol H+/ml medium 
pH stability, operational14–12 
pH stability, CIP23–14 
Pressure/Flow Specification300 kPa at min. 220 cm/h, 1 m diameter column, 20 cm bed height 
Storage4 to 30°C, 20% Ethanol + 0.2 M Sodium Acetate 
Chemical stabilityCommonly used aqueous buffers, 1 M NaOH, 8 M urea, 6 M guanidine hydrochloride, 30% isopropanol and 70 % ethanol 
Avoid UsingOxidizing agents, cationic detergents 
Certificate of AnalysisYes 
Pack size1 L 
  • 1pH range where resin can be operated without significant change in function.
  • 2pH range where resin can be subjected to cleaning- or sanitization-in-place without significant change in function.
商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16