尿素酶来源于洋刀豆 [脲酶]，Urease from Canavalia ensiformis (Jack bean)；Type IX, powder, 50,000-100,000 units/g solid

General description

Urease (Ure) enzyme is present in the cytosol. It is active at acidic pH and is expressed at 28°C.^[2] Urease binds to nickel and is present in archaea, bacteria, unicellular eukaryotes and plants.^[3] Jack bean urease was the first enzyme to be crystallized and the first enzyme found to contain nickel.^[7] It is a multi-subunit enzyme, consisting of 91 kDa subunits in three protein forms.

亚基分子量：约 90,770
由六个亚基组成，总分子量：约 544620

Application

Urease from Canavalia ensiformis (Jack bean) has been used: to spike urine samples to determine the hydrolysis rate of urea in pure urine^[4] It has also been used to study the inhibitory action of polyhalogenated benzo- and naphthoquinones on Bacillus pasteurii and Canavalia ensiformis.^[5]

包装

20000, 100000, 500000, 1000000 units in poly bottle

Biochem/physiol Actions

Urease is involved in purine metabolism and the urea cycle. It hydrolyze urea to produce ammonia and carbon dioxide.^[6]

在洋刀豆（Jack Bean）中，脲酶促进L-刀豆氨酸转化为副刀豆氨酸。 ^[1]

Unit Definition

一微摩尔单位是指在pH 7.0，25℃下每分钟催化尿素释放1.0 μM NH₃所需的酶活性。它相当于1.0 I.U.或0.054 Sumner单位（在pH 7.0，20°C，5分钟内产生1.0 mg氨氮）

性质

安全信息

符号

  GHS07,GHS08

信号词 Danger

危害声明 H315 - H319 - H334 - H335

警示性声明 P261 - P264 - P271 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338

靶器官 Respiratory system

危害码 (欧洲) Xn

风险声明 (欧洲) 36/37/38-42

安全声明 (欧洲) 22-24-26-36/37

RIDADR NONH for all modes of transport

WGK德国 WGK 1