General description
一种胆酸的新衍生， 是FXR（ 胆汁酸受体）激动剂，EC50：99nM。
Obeticholic Acid is a novel derivative of cholic acid which acts as a potent and selective FXR agonist displaying anticholeretic activity in an in vivo rat model of cholestasis. It inhibits vascular smooth muscle cell inflammation and migration as well as promotes adipocyte differentiation and regulates adipose cell function in vivo。
奥贝胆酸是胆酸的一种新型衍生物，在胆汁淤积症的体内大鼠模型中，它发挥有效的选择性FXR激动剂的作用，显示出抗胆汁的活性。 它可以抑制血管平滑肌细胞的炎症和迁移，并促进体内脂肪细胞的分化和调节脂肪细胞的功能。
Properties
| Iupac Name： | (3alpha,5beta,6alpha,7alpha)-6-ethyl-3,7-dihydroxycholan-24-oic acid |
| Inchi Code | 1S/C26H44O4/c1-5-17-21-14-16(27)10-12-26(21,4)20-11-13-25(3)18(15(2)6-9-22(28)29)7-8-19(25)23(20)24(17)30/h15-21,23-24,27,30H,5-14H2,1-4H3,(H,28,29)/t15-,16-,17-,18-,19+,20+,21+,23+,24-,25-,26-/m1/s1 |
| Inchi Key | ZXERDUOLZKYMJM-ZWECCWDJSA-N |
安全信息
迷迭香酸，Rosmarinic acid；96%![图片 盐酸胍，Guanidine hydrochloride [GdnHCl]；≥99.0% (AT)](https://www.bszh.cn/images/thumbs/0004351_guanidine-hydrochloride-gdnhcl990-at_32.png "显示明细 盐酸胍，Guanidine hydrochloride [GdnHCl]；≥99.0% (AT)")
盐酸胍，Guanidine hydrochloride [GdnHCl]；≥99.0% (AT)
1,2,3-苯三甲酸，Benzene-1,2,3-tricarboxylic acid![图片 抑肽酶来源于牛肺，Aprotinin from bovine lung [BPTI]；lyophilized, ~80% (HPCE), crystalline (fine), white, ≥3500 U/mg](https://www.bszh.cn/images/thumbs/0004874_aprotinin-from-bovine-lung-bptilyophilized-80-hpce-crystalline-fine-white-3500-umg_32.jpeg "显示明细 抑肽酶来源于牛肺，Aprotinin from bovine lung [BPTI]；lyophilized, ~80% (HPCE), crystalline (fine), white, ≥3500 U/mg")
抑肽酶来源于牛肺，Aprotinin from bovine lung [BPTI]；lyophilized, ~80% (HPCE), crystalline (fine), white, ≥3500 U/mg
胃蛋白酶来源于猪胃粘膜，Pepsin from porcine gastric mucosa；tested according to Ph. Eur.
胰酪蛋白胨，Pancreatic casein peptone