IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant rat IL-2 is a 15.3 kDa protein containing 134 amino acid residues.
IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. Recombinant rat IL-2 is a 15.3 kDa protein containing 134 amino acid residues.
MAPTSSPAKE TQQHLEQLLL DLQVLLRGID NYKNLKLPMM LTFKFYLPKQ ATELKHLQCL ENELGALQRV LDLTQSKSFH LEDAGNFISN IRVTVVKLKG SENKFECQFD DEPATVVEFL RRWIAIAQSI ISTM
Lyophilized from 10 mM Sodium Citrate, pH 4.0.
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
|biological source ||rat|
|recombinant ||expressed in E. coli|
|assay ||≥98% (HPLC)|
| ||≥98% (SDS-PAGE)|
|potency ||≤0.4 ng/mL ED50|
|mol wt ||15.3 kDa|
|packaging ||pkg of 20 μg|
|application(s) ||cell culture | mammalian: suitable|
|impurities ||<0.1 EU/μg endotoxin, tested|
|color ||white to off-white|
|UniProt accession no. ||P17108|
|shipped in ||wet ice|
|storage temp. ||−20°C|
|Gene Information ||rat ... IL2(116562)|
RIDADR NONH for all modes of transport