大分子离子交换层析树脂,Capto Q XP ion exchange chromatography resin

Capto Q XP 设计用于下游工艺中大生物分子(例如免疫球蛋白 IgG、IgM、IgA)的捕获和中间纯化。17547302;17547301;17547304;17547303
货号(SKU): 17547303
增值税发票 √ 免费送货 √ 订货电话:010-68689484

Capto Q XP is designed for capture and intermediate purification of large biomolecules, such as immunoglobulins IgG, IgM, IgA, in downstream processes.

基于成熟的 Capto 平台和传统配体进行高效的工业规模纯化。
Resin 满足工业对供应安全性、强大性能和监管支持的需求。
Capto Q XP 基于高流量琼脂糖基质,具有良好的压力流动特性和宽孔开口,可为大生物分子的吸附提供高可用表面积。树脂的 Q 配体在大规模纯化中得到了很好的证实。

基础基质的特性与常规 Q 配体相结合,使 Capto Q XP 成为大生物分子的高生产率捕获和中间纯化的绝佳选择。

Capto Q XP 提供了简单的工艺开发和许多提高工业规模生产力的机会。

  • Efficient industrial-scale purification based on the well-established Capto platform with traditional ligands.
  • Flexible process design due to large operational window of flow rates and bed heights.
  • High throughput to improve manufacturing productivity and process economy.
  • Excellent chemical stability.
  • Resin fulfills industrial demands for security of supply, robust performance, and regulatory support.

Useful for large biomolecules

Capto Q XP is based on a high-flow agarose base matrix with good pressure-flow properties and wide pore openings to give high available surface area for adsorption of large biomolecules. The Q ligand of the resin is well-established in large-scale purifications.

The features of the base matrix, in combination with the conventional Q ligand, make Capto Q XP an excellent choice for high-productivity capture and intermediate purification of large biomolecules.

Suited to large-scale production

Capto Q XP provides straightforward process development and many opportunities for improved productivity in industrial scales.

Prepacked columns and other formats

Capto Q XP is available in the following formats: 

Lab/research scale – prepacked for manual purification

HiTrap Capto Q XP columns – for easy use with a syringe, peristaltic pump, or chromatography system

Lab/research scale – prepacked for automated purification and analysis

HiTrap Capto Q XP columns – for easy use with a syringe, peristaltic pump, or chromatography system.


ParameterCapto Q XP 1 L
Chromatography techniqueIon Exchange Chromatography 
BioProcess resinYes 
Particle size, d50V1~75 μm 
Ion Exchanger TypeStrong anion exchanger 
MatrixHigh-flow agarose 
Ionic Capacity95 to 125 µmol Cl-/mL resin 
pH stability, operational22–12 
pH stability, CIP32–14 
Pressure/Flow Specification0.3 MPa at 700 cm/h, 1 m diameter column, 20 cm bed height 
Flow velocityUp to 300 cm/h in a 1 m diameter column with bed height 20 cm at 20°C; measured using process buffers with the same viscosity as water at < 3 bar (0.3 MPa) 
Storage20% ethanol at 4°C to 30°C 
Estimated shelf life from manufacture date5 years 
Chemical stabilityCommonly used aqueous buffers: 1 M sodium hydroxide, 8 M urea, 6 M guanidine hydrochloride, 30% isopropanol, and 70% ethanol 
Pack size1 L 
  • 1d<sub>50V</sub> is the median particle size of the cumulative volume distribution.
  • 2pH range where resin can be operated without significant change in function.
  • 3pH range where resin can be subjected to cleaning- or sanitization-in-place without significant change in function.
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16