复合模式多峰层析树脂,Capto Core 700 multimodal chromatography resin

新型核心珠技术和多峰辛胺配体赋予 Capto Core 700 双重功能。 这种层析树脂同时具有尺寸排阻和结合特性。17548103;17548102;17548101;17548104
货号(SKU): 17548103
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Novel core bead technology and multimodal, octylamine ligand give Capto Core 700 dual functionality. This chromatography resin has both size exclusion and binding properties.

新型核心珠技术和多峰辛胺配体赋予 Capto Core 700 双重功能。这种层析树脂同时具有尺寸排阻和结合特性。
使用预装 HiTrap 和 HiScreen 色谱柱方便的小规模纯化、工艺开发和放大。
Resin 满足工业对供应安全性、强大性能和监管支持的需求。
Capto Core 700 由配体激活的核心和非活性壳组成。非活性壳阻止大分子(截止到 700 000 先生)通过壳孔进入核。这些较大的分子被收集在柱流穿中,而较小的杂质则与内化的配体结合。


ParameterCapto Core 700, 1 L
BioProcess resinYes 
Particle size, d50V1~90 µm 
MatrixHighly cross-linked agarose 
Binding Capacity/ml Chromatography Medium2~ 13 mg ovalbumin 
Ionic Capacity40-85 µmol/ml (Cl-
pH stability, operational33–13 
pH stability, CIP42–14 
Flow velocity5< 500 cm/h 
Storage4 to 30°C, 20% Ethanol 
Chemical stability6Commonly used aqueous buffers,1 M sodium hydroxide6, 6 M guanidine hydrochloride, 30% isopropanol, and 70% ethanol 
Avoid Using7Oxidizing agents, citrate buffers 
Molecular Weight (MW) Cut-OffMr ~700 000 
Pack size1 L 
  • 1Median particle size of the cumulative volume distribution.
  • 2Dynamic binding capacities were measured at 10% breakthrough with a residence time of 3 min (1.6 mL/min = 200 cm/h) in HiScreen columns. Buffer: 20 mM Tris-HCl, 150 mM NaCl, pH 7.5.
  • 3pH range where resin can be operated without significant change in function.
  • 4pH interval where the medium can be subjected to, for cleaning- or sanitization-in-place.
  • 5Water at room temperature. For viscous buffers and samples - the flow velocity must be optimized and starting with a low flow rate is recommended in order not to exceed pressure limits.
  • 6No significant change in ionic binding capacity and carbon content after one week storage in 1 M NaOH at 40°C.
  • 7Citrate ions are trivalent anions and can interact with the positively charged octylamine ligand on Capto Core 700.
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 99 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 22 | 香港与北京 ≥ 32