填充床亲和层析树脂,Alpha-1 Antitrypsin Select

Alpha-1 Antitrypsin Select是一种填充床亲和层析树脂,对 AAT 具有高选择性。 它可用于从血浆(包括 Cohn 级分)以及重组或转基因来源中纯化人 AAT。 在第一个捕获步骤中,Alpha-1 Antitrypsin Select 提供高纯度和产量。 该树脂还可用于中间纯化/抛光以提高产品纯度。17547203;17547202;17547201;17547204
货号(SKU): 17547203
增值税发票 √ 免费送货 √ 订货电话:010-68689484

用于高效工业纯化 alpha-1 抗胰蛋白酶 (AAT) 的高选择性亲和层析树脂
在中性 pH 条件下温和的洗脱条件
Alpha-1 Antitrypsin Select 是一种填充床亲和层析树脂,对 AAT 具有高选择性。 它可用于从血浆(包括 Cohn 级分)以及重组或转基因来源中纯化人 AAT。 在第一个捕获步骤中,Alpha-1 Antitrypsin Select 提供高纯度和产量。 该树脂还可用于中间纯化/抛光以提高产品纯度。

  • Affinity chromatography resin with high selectivity for efficient industrial purification of alpha-1 antitrypsin (AAT)
  • Outstanding pressure and flow rates reduce process times and improve process economy
  • Mild elution conditions at neutral pH
  • The hydrophilic nature of the base matrix ensures low levels of non-specific binding.

Alpha-1 Antitrypsin Select is a packed-bed affinity chromatography resin with high selectivity for AAT. It can be used for purifying human AAT from plasma (including Cohn fractions), as well as from recombinant or transgenic sources. In a first capture step, Alpha-1 Antitrypsin Select gives high purity and yield. The resin can also be used in intermediate purification/polishing to enhance product purity.


ParameterAlpha-1 Antitrypsin Select, 1 L
BioProcess resinYes 
LigandAlpha-1 antitrypsin binding ligand  
Particle size, d50V1~75 μm 
MatrixHighly cross-linked spherical agarose 
Binding Capacity/ml Chromatography Medium2Approx. 10 mg alpha-1 antitrypsin/mL resin 
Ligand densityApprox. 5.5 mg/ml of medium 
pH stability, operational33–10 
pH stability, CIP42–11 
Storage20% ethanol in water 
Chemical stabilityStable in commonly used aqueous buffers 
Pack size1 L 
  • 1Median particle size of the cumulative volume distribution.
  • 2Determined using a total capacity chromatography method
  • 3pH range where resin can be operated without significant change in function.
  • 4Short-term refers to the pH interval for regeneration and cleaning
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 99 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 22 | 香港与北京 ≥ 32