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地塞米松,Dexamethasone [DXMS];meets USP testing specifications, 97.0-102.0%

别名:德沙美松;21α-乙酰氧基-9α-氟-11β,17α-二羟基-16α-甲基孕甾-1,4-二烯-3,20-二酮;9α-氟-16α-甲基氢化泼尼松;9-氟-11,17,21-三羟基-16-甲基(11b,16a)-孕甾-1,4-二烯-3,20-二酮;(11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, Prednisolone F

CAS号 50-02-2 经验分子式(希尔表示法) C22H29FO5 分子量 392.46 Beilstein/REAXYS Number 2066651 EINECS 编号 200-003-9 MDL number MFCD00064136 PubChem Substance ID 24894273 NACRES NA.21
货号(SKU): D9184
CAS号: 50-02-2
MDL号: MFCD00064136
增值税发票 √ 免费货运 [顺丰 联邦] √
¥916.00

产品描述

General description

一种抗炎糖皮质素,对细胞存活、细胞信号传导和基因表达具有一系列的影响。用于研究细胞凋亡、细胞信号传导通路和基因表达。

Application

Dexamethasone was used as medium supplement in the following studies:
• To investigate the osteogenic differentiation and chondrogenic differentiation of bone marrow mesenchymal stem cells (MSCs).[2]
• In α-MEM (minimum essential medium) for inducing the osteogenic and adipogenic differentiation in mesenchymal stem cells from human bone marrow and umbilical cord blood.[1]
• For the isolation and characterization of mesenchymal stem cells isolated from 6- to 8-week-old C57BL/6J mice.[3]

包装

1, 5 g in glass bottle

100 mg in glass bottle

Biochem/physiol Actions

糖皮质素抗炎剂。调控 T 细胞的存活、生长和分化。抑制一氧化氮合酶的诱导作用

性质

Quality Level200
biological sourcesynthetic (organic)
assay97.0-102.0%
formsolid
mp262-264 °C (lit.)
suitabilitymeets USP testing specifications
shipped inambient
storage temp.2-8°C
SMILES stringC[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
InChI1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
InChI keyUREBDLICKHMUKA-CXSFZGCWSA-N
Gene Informationhuman ... ABCB1(5243), CYP3A4(1576), IL4(3565), IL5(3567), NR3C1(2908)
mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126), Ptgs2(19225), Tnf(21926)
rat ... Ar(24208), Nr3c1(24413), Tnf(24835)


安全信息

符号
GHS08  GHS08
信号词 Danger
危害声明 H360D
警示性声明 P201-P280-P308 + P313
危害码 (欧洲) Xn
风险声明 (欧洲) 36/37/38-42/43
安全声明 (欧洲) 22-26-36/37-45
RIDADR NONH for all modes of transport
WGK德国 2
RTECS TU3980000
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 88 | 欧洲Eur. ≥ 126 | 東京Tokyo ≥ 46 | 香港与北京 ≥ 62
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