化学结构:四环素四环素是一种广谱聚酮类抗生素,临床用于治疗细菌感染,如落基山斑点热、typush热、蜱热、Q热和Brill-Zisser病,以及治疗上呼吸道感染和痤疮。它已用于多药耐药性和潜在副作用的研究,包括急性胰腺炎。建议在10 mg/L的细胞培养应用中使用。
synthetic
200
USP/NFmeets USP testing specifications
solid
[α]/D -255 to 240° (Specific rotation )
(Keep container tightly closed in a dry and well-ventilated place. Light sensitive.)
220-223 °C (lit.)
Gram-negative bacteriaGram-positive bacteria
pharmaceutical (small molecule)
protein synthesis | interferes
−20°C
Cl.CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O
1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
XMEVHPAGJVLHIG-FMZCEJRJSA-N
Warning
Aquatic Acute 1 - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
Respiratory system
11 - Combustible Solids
WGK 2
dust mask type N95 (US), Eyeshields, Gloves