噻康唑，Tioconazole；97%

别名：1-[2-[(2-氯-3-噻吩基)甲氧基]-2-(2,4-二氯苯基)乙基]-1H咪唑；硫代环唑；1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, Thioconazole

Empirical Formula (Hill Notation): C16H13Cl3N2OS CAS号: 65899-73-2 分子量: 387.71 EC 号: 265-973-8 MDL编号: MFCD00057276 PubChem化学物质编号: 329747834 NACRES: NA.85

制造商品牌: 西格玛 Sigma-Aldrich

货号（SKU）: 03907

CAS号: 65899-73-2

MDL号: MFCD00057276

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目录价.SKU-Variant

10g
25g [+¥1,736.06]

¥1,414.66

数量:

说明

化学结构：嘧啶
使用替康唑研究了抗真菌药物对白色念珠菌的协同作用机制以及体内显著的药物相互作用。
替康唑是咪唑类抗真菌药物，用于治疗真菌和酵母菌引起的感染。它比氟康唑或伏立康唑对光滑念珠菌突变株更具活性。它通过膜破裂和细胞内ATP的损失而起作用。

一般描述

Chemical structure: pyrimidine

应用

Tioconazole was used to study the synergistic mechanisms of antifungals on Candida albicans as well as significant drug-drug interactions in vivo.

生化/生理作用

Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by fungus and yeast.It is more active than fluconazole or voriconazole against Candida glabrata mutant strains. It acts by membrane disruption and loss of intracellular ATP.

其他说明

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 03907.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

属性

质量水平

100

测定

≥96.5% (HPLC)
96.5-103.5% (NT)
97%

形式

powder

颜色

white to off-white

抗生素抗菌谱

fungi
yeast

作用机制

cell membrane | interferes

SMILES string

Clc1ccc(C(Cn2ccnc2)OCc3ccsc3Cl)c(Cl)c1

InChI

1S/C16H13Cl3N2OS/c17-12-1-2-13(14(18)7-12)15(8-21-5-4-20-10-21)22-9-11-3-6-23-16(11)19/h1-7,10,15H,8-9H2

InChI key

QXHHHPZILQDDPS-UHFFFAOYSA-N

安全信息

象形图

GHS07,GHS08,GHS09

警示用语：

Warning

危险声明

H302 - H317 - H361d - H410

预防措施声明

P202 - P273 - P280 - P301 + P312 - P302 + P352 - P308 + P313

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

商品规格

属性名称	属性值
储存温度 Storage temp.	2-8°C冷藏
全球实时库存 Availability √	美国St. Louis ≥ 99 \| 欧洲Eur. ≥ 10 \| 東京Tokyo ≥ 22 \| 香港与北京 ≥ 32

商品标签 [tags]

噻康唑 (2)