叔戊氧基钾溶液，Potassium tert-pentoxide solution；2 M in THF

图片 叔戊氧基钾溶液，Potassium tert-pentoxide solution；2 M in THF
别名：2-甲基-2-丁醇钾；叔戊醇钾；Potassium (2-methyl-2-butoxide), Potassium tert-pentylate

线性分子式: CH3CH2C(CH3)2OK CAS号: 41233-93-6 分子量: 126.24 Beilstein: 4149025 MDL编号: MFCD00064808 PubChem化学物质编号: 329762401 NACRES: NA.22
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: 702757
CAS号: 41233-93-6
MDL号: MFCD00064808
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说明

一般描述

Potassiumtert-pentoxide solution is a strong and sterically hindered alkoxide baseprepared by treating oil-free potassium hydride with anhydrous t-pentylalcohol in anhydrous solvent.
 

应用

Potassium tert-pentoxide solution can be used as a base in the:
  • Wittig reaction of ketoesters with methyltriphenylphosphonium bromide to synthesize alkenes.
  • Palladium-catalyzed Buchwald-Hartwig amination reaction.
It can also be used:
  • To prepare potassium tert-pentoxide-crown ether complexes, which is used as a Lewis base catalyst in Mukaiyama aldol reaction.
  • As an activator for (difluoromethyl)trimethylsilane to generate difluoromethyl-carbanion which reacts with isothiocyanate to synthesize α, α-difluoromethyl thioamide.

特点和优势

In the absence of air and moisture, potassium tert-pentoxide solutions in benzene or toluene may be stored in a refrigerator for up to 1 year without significant deterioration.
 
 

属性

形式

liquid

浓度

2 M in THF

密度

0.920 g/mL at 25 °C

SMILES string

[K+].CCC(C)(C)[O-]

InChI

1S/C5H11O.K/c1-4-5(2,3)6;/h4H2,1-3H3;/q-1;+1

InChI key

ZRLVQFQTCMUIRM-UHFFFAOYSA-N

 

安全信息

警示用语：

Danger

危险分类

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

补充剂危害

EUH019

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(F)

1.4 °F - Solvent

闪点(C)

-17 °C - Solvent

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 50 | 欧洲Eur. ≥ 12 | 東京Tokyo ≥ 20 | 香港与北京 ≥ 50
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