双酚A (3-氯-2-羟丙基) (2,3-二羟基丙基)醚，Bisphenol A (3-chloro-2-hydroxypropyl) (2,3-dihydroxypropyl) ether [EPI-001, BADGE-HCl]；≥98% (HPLC)

图片 双酚A (3-氯-2-羟丙基) (2,3-二羟基丙基)醚，Bisphenol A (3-chloro-2-hydroxypropyl) (2,3-dihydroxypropyl) ether [EPI-001, BADGE-HCl]；≥98% (HPLC)
别名：2-[4-(3-氯-2-羟基丙氧基)苯基]-2-[4-(2,3-二羟基丙氧基)苯基]丙烷；BADGE-HCl-H2O, 2-[4-(3-Chloro-2-hydroxypropyloxy)phenyl]-2-[4-(2,3-dihydroxypropyloxy)phenyl]propane；3-[4-[1-[4-(3-Chloro-2-hydroxypropoxy)phenyl]-1-methylethyl]phenoxy]-1,2-propanediol, EPI001

Empirical Formula (Hill Notation): C21H27ClO5 CAS号: 227947-06-0 分子量: 394.89 MDL编号: MFCD02683414 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: SML1844
CAS号: 227947-06-0
MDL号: MFCD02683414
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说明

生化/生理作用

EPI-001 is a specific inhibitor of the AR (androgen receptor) without inhibiting PR or GR transcriptional activities. EPI-001 selectively interacts with transactivation unit 5 (Tau-5) of the androgen receptor, which is essential for prostate cells to proliferate in the absence of androgens. EPI-001 is active against castration-resistant prostate cancer (CRPC) in xenografts.
 
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

颜色

white to beige

溶解性

DMSO: 15 mg/mL, clear

储存温度

−20°C

 

安全信息

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315 - H319 - H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 30 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 30
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