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利巴韦林,Ribavirin [病毒唑];Pharmaceutical Secondary Standard; Certified Reference Material [药物标准品]

别名:1-β-D-呋喃核糖基-1,2,4-三唑-3-甲酰胺;1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide;1-β-D-呋喃核糖-1,2,4-三氮唑-3-羟酰胺;三氮唑核苷; 1-beta-D-呋喃核糖基-1H-1,2,4,-三氮唑-3-羧酰胺;三唑核苷;病毒唑;威乐星

CAS号 36791-04-5 经验分子式(希尔表示法) C8H12N4O5 分子量 244.20 MDL number MFCD00058564 PubChem Substance ID 329823563
货号(SKU): PHR1700
CAS号: 36791-04-5
MDL号: MFCD00058564
增值税发票 √ 免费货运 [顺丰 联邦] √
$252.77

产品描述

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards

Ribavirin is a synthetic guanosine analog, effective against respiratory syncytial virus, several hemorrhagic fever viruses and human immuno deficiency virus.[1]

嘌呤核苷酸生物合成中咪唑核苷酸中间体的类似物。

Application

Ribavirin may be used as a pharmaceutical reference standard for the determination of the analyte in drug dosage forms by high-pressure liquid chromatographic method.[2]

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

用于抵御多种人类病毒感染的抗病毒剂,特别是慢性肝炎C、HIV 和腺病毒。其代谢产物利巴韦林 5′-磷酸,是肌苷一磷酸 (IMP) 脱氢酶的抑制剂,但也有实验证据支持许多其他作用机制

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA6966 in the slot below. This is an example certificate only and may not be the lot that you receive.

性质

Quality Level300
gradecertified reference material
pharmaceutical secondary standard
packagingpkg of 1 g
application(s)HPLC: suitable
gas chromatography (GC): suitable
Featured IndustryPharmaceutical (small molecule)
formatneat
pharmacopeia traceabilityPhEur
traceable to BP 593
traceable to USP 1602706
SMILES stringNC(=O)c1ncn(n1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O
InChI1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1
InChI keyIWUCXVSUMQZMFG-AFCXAGJDSA-N
Gene Informationhuman ... IMPDH1(3614)


安全信息

符号
GHS08  GHS08
信号词 Danger
危害声明 H341 - H360FD
警示性声明 P201 - P308 + P313
危害码 (欧洲) T
风险声明 (欧洲) 61
安全声明 (欧洲) 53-22-45
RIDADR NONH for all modes of transport
WGK德国 WGK 3
RTECS XZ4250000
闪点(华氏) Not applicable
闪点(摄氏) Not applicable
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 190 | 欧洲Eur. ≥ 66 | 東京Tokyo ≥ 82 | 香港与北京 ≥ 55
商品标签