过滤
关闭导航

冬凌草甲素,Oridonin;phyproof® Reference Substance, ≥98.0% (HPLC)

一种可渗透细胞的二萜化合物,具有抗 NF-κB 活性并具有抗增殖和抗血管生成特性.

别名:Isodonol, 7a,20-Epoxy-1a,6b,7,14-tetrahydroxy-Kaur-16-en-15-one; Empirical Formula (Hill Notation): C20H28O6 CAS号: 28957-04-2 分子量: 364.43
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): PHL89745
CAS号: 28957-04-2
MDL号: MFCD00221762
增值税发票 √ 免费送货 √ 订货电话:010-68689484
¥3,919.29

说明

一般描述

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
 

生化/生理作用

Oridonin has potent anti-tumor activity. Oridonin targets AE (AML1-ETO) oncoprotein. Exposure to oridonin induces apoptosis in AE-bearing leukemic cells through the activation of intrinsic apoptotic pathway and triggering a caspase-3-mediated degradation of AE at D188. The compound also prolonged the lifespan of C57 mice bearing truncated AE-expressing leukemic cells without side effects like suppression of bone marrow or reduction of body weight of animals, and exerted synergic effects while combined with cytosine arabinoside. Additionally, oridonin inhibited tumor growth in nude mice inoculated with t(8;21)-harboring Kasumi-1 cells.
 

法律信息

phyproof is a registered trademark of PhytoLab GmbH & Co. KG
 
 

属性

等级

primary reference standard

产品线

phyproof® Reference Substance

测定

≥98.0% (HPLC)

manufacturer/tradename

PhytoLab

application(s)

food and beverages

格式

neat

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16
商品标签 [tags]