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假尿苷,Pseudouridine;≥98%

别名:伪尿苷;β-假尿苷;假尿甙;ψ-尿苷;5-(β-D-核呋喃基)尿嘧啶;Pseudouridine, β-Pseudouridine, ψ-Uridine, 5-(β-D-Ribofuranosyl)uracil

Empirical Formula (Hill Notation): C9H12N2O6 CAS号: 1445-07-4 分子量: 244.20
制造商品牌: Sigma-Aldrich
货号(SKU): SMB00912
CAS号: 1445-07-4
MDL号: MFCD00038458
技术支持 √ 增值税发票 √ 免费送货 √ 质量保障 √
¥937.87

说明

一般描述

伪尿苷是一种C-糖基嘧啶,由尿嘧啶组成,尿嘧啶在位置5处连接有β-D-呋喃呋喃糖基残基。嘧啶核苷尿苷的C-糖基异构体。它具有基本代谢物的作用。假尿苷存在于除mRNA以外的所有物种和所有类别的RNA中。它由称为假尿苷合酶的酶形成,该酶在转录后异构化RNA中的特定尿苷残基。
Pseudouridine (Ψ) stands as an isomer of the nucleoside uridine, featuring a carbon-carbon bond instead of the typical nitrogen-carbon glycosidic bond connecting uracil. It represents the most prevalent among the myriad modified nucleosides within RNA, with a presence spanning various species and RNA classes. The enzymatic action of Ψ synthases induces post-transcriptional isomerization of specific uridine residues, a process known as pseudouridylation. This modification, particularly in rRNA and tRNA, plays a vital role in fine-tuning and stabilizing regional structures, contributing to mRNA decoding, ribosome assembly, processing, and translation functions. Moreover, β-pseudouridine, identified in tRNAs across bacteria, archaea, and eukaryotes, has demonstrated potential in reducing radiation-induced chromosome aberrations in human lymphocytes. Its utility as a cancer and proliferation biomarker positions it as a valuable asset in metabolomics and biochemical research.
 

应用

Pseudouridine is a versatile compound and a biomarker that finds application in metabolomics and biochemical research.
 

特点和优势

  • High-purity compound suitable for a wide variety of research applications

其他说明

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
 
 

属性

检测方案

≥98%

形式

powder

颜色

white to off-white

mp

222 °C ((432 °F ))

溶解性

water: soluble

储存温度

2-8°C

InChI

1S/C9H12N2O6/c12-2-4-5(13)6(14)7(17-4)3-1-10-9(16)11-8(3)15/h1,4-7,12-14H,2H2,(H2,10,11,15,16)/t4-,5-,6-,7+/m1/s1

InChI key

PTJWIQPHWPFNBW-GBNDHIKLSA-N

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16