<br /> Empirical Formula (Hill Notation): C22H29FO5 CAS号: 378-44-9 分子量: 392.46 EC 号: 206-825-4 MDL编号: MFCD00062969 PubChem化学物质编号: 57653954 NACRES: NA.77">
倍他米松已被用作皮质类固醇(CORT)标准。地塞米松的异构体倍他米松也称为9α-氟-16β-甲基-11β,17,21-三羟基孕烷-1,4-二烯-3,20-二酮或9α-氟-16β-甲基强的松龙(27.1.52)。它可以用作抗瘙痒剂并治疗皮炎和湿疹。
synthetic (organic)
100
non-sterile
≥98%
powder
235-237 °C (lit.)
water: 0.063 g/L at 37 °C
ambient
room temp
[H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
UREBDLICKHMUKA-DVTGEIKXSA-N
human ... ABCB1(5243) , CYP3A4(1576) , IL4(3565) , IL5(3567) , NR3C1(2908)mouse ... Abcb1a(18671) , Abcb1b(18669) , Ifng(15978) , Nos2(18126) , Tnf(21926)rat ... Ar(24208) , Nr3c1(24413) , Tnf(24835)
Danger
Repr. 1B - STOT RE 2
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK 2
Eyeshields, Gloves, type N95 (US)