依西美坦，Exemestane；Pharmaceutical Secondary Standard; Certified Reference Material

图片 依西美坦，Exemestane；Pharmaceutical Secondary Standard; Certified Reference Material
别名：依西美坦标准品；6-亚甲基-雄-1,4-二烯-3,17-二酮；6-Methyleneandrosta-1,4-diene-3,17-dione

Empirical Formula (Hill Notation): C20H24O2 CAS号: 107868-30-4 分子量: 296.40 MDL编号: MFCD00866994 PubChem化学物质编号: 329823524 NACRES: NA.24
制造商品牌: 色谱科 Supelco , 西格玛 Sigma-Aldrich
货号（SKU）: PHR1634
CAS号: 107868-30-4
MDL号: MFCD00866994
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √

说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Exemestane is a steroidal anticancer drug, that belongs to the class of antiestrogens known as aromatase inhibitors. It is commonly used for the treatment of breast cancer.[1]
 

应用

Exemestane may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by chromatography.[2][3]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
 

生化/生理作用

Exemestane is a steroidal antiestrogen and irreversible aromatase inhibitor. Exemestane acts as a false substrate for the aromatase enzyme. Exemestane also prevents the conversion of androgens to estrogens and is used to treat estrogen-dependent breast cancer.
 

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
 

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
 

附注

To see an example of a Certificate of Analysis for this material enter LRAC3262 in the slot below. This is an example certificate only and may not be the lot that you receive.
 
 

属性

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to USP 1269050

API family

exemestane

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES string

C[C@]12CC[C@H]3[C@@H](CC(=C)C4=CC(=O)C=C[C@]34C)[C@@H]1CCC2=O

InChI

1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1

InChI key

BFYIZQONLCFLEV-DAELLWKTSA-N

Gene Information

human ... CYP19A1(1588)

 

安全信息

象形图

Health hazardEnvironment
GHS08,GHS09

警示用语：

Danger

危险声明

H360 - H411

危险分类

Aquatic Chronic 2 - Repr. 1B

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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